Kelch stimulates dendritic elaboration in a Cullin3-dependent manner.

<p>(A, F, K, P) MARCM clones of wild type ddaC, ddaA, ddaB, ddaF neurons, respectively. (B, G, L, Q) MARCM clones of <i>UAS-Kelch</i> in these types of neurons, Kelch overexpression stimulates dendritic branching. (C, H, M, R) Double clones of <i>cul3</i> and <i>UAS-Kelch</i> in ddaC, ddaA, ddaB, ddaF neurons. Simultaneous Kelch overexpression and loss of Cullin3 function resulted in increased branching phenotypes, especially in ddaB (M) and ddaF (R) neurons. Scale bar: 50 µm. (D, I, N, S) Quantifications of terminal dendritic ends in wild type, <i>UAS-Kelch</i>, and <i>cul3 UAS-Kelch</i> double clones in ddaC, ddaA, ddaB, ddaF neurons, respectively. (E, J, O, T) Quantifications of total dendritic length in wild type, <i>UAS-Kelch</i>, and <i>cul3 UAS-Kelch</i> double clones in ddaC, ddaA, ddaB, ddaF neurons, respectively. ***: p<0.001, **: p<0.01, *: p<0.02.