Arl2 content influences tumorigenesis.

<p>A: Representative images of non invasive bioluminescent follow up (from day 17 to day 36) for a same tumor of each cell lines (MdaA-.luc, MdaP.luc, MdaA+.luc) developed from mice mammary fat pad injected cells. B: Mean rates of tumoral bioluminescence in mice expressed in photons/sec for each day and sublines. Tumor growths (R-growths) were evaluated using a linear projection of the growth curve (red) and expressed in arbitrary units per day (AU/day). Bars represent standard deviations. Statistical significance was determined using Student's t test. C: Representative images of histochemistry of MdaA-, MdaP, MdaA+ cells tumors slides at day 22, 29 and 36. Black arrows show necrotic regions (in light pink) which are particularly important in MdaA+ cells tumors.