EBNA1 binding to DNA is stimulated by USP7.

<p>A. Schematic representation of EBNA1 and the EBNA1 mutants used in this study. Shown are the Gly-Ala repeat (GA), the large Gly-Arg repeat (GR), the USP7 binding site (USP7) and the flanking and core DNA binding domains. B and C. EMSAs showing titrations of EBNA1 (B) or EBNA1_452–641 (C) with a fixed amount of DNA recognition site in the presence or absence of 10 pmols of USP7 or in the presence or absence of 10 pmols BSA as a negative control (B, right panel).