Experimental TSEs transmission results to TgOvPrP4 ovine transgenic mice.

(1)<p>Animals were inoculated intracerebrally with 2 mg brain tissue.</p>(2)<p>Genotype of sheep or goat (amino acids 136, 141, 154, and 171).</p><p>Experimental inoculums were divided into 2 different groups. Group 3: small ruminants intracerebrally inoculated with various TSEs. Group 4: experimental strains initially derived from wild-type mice. Detection of PrP^res/PrP^sc was performed by Western blot or IHC analyses.