Trehalose stabilization of vaccine improves protective efficacy.

<p>At week 5 after a single vaccination, mice (n = 12) were challenged with a lethal dose (A/PR8 virus, 20× LD50) and were monitored daily to record body weight changes (A) and survival rates (B). Groups of mice are described as in the legend of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007152#pone-0007152-g002" target="_blank">Fig. 2</a>.