MβCD treatment blocks activation of EGF receptors.

<p>A,B: Labeling with an antibody to the EGF receptor (red) that recognizes the receptor regardless of activation state. The receptor is present on ORN axons in both control (A) and MβCD-treated (B) animals. Glial cells beginning to form envelopes (arrowheads) around protoglomeruli in panel A. C,D: Labeling with an antibody to the activated EGF receptor (red) shows labeling in the SZ and developing glomeruli in controls (C), but not in MβCD-treated animals (D).