Reduction of platelet surface CD47 expression in mice treated with CCF from STEC O157:H7 (strain 99G144).

<p>A, CD47 expression on platelet surfaces measured by flow cytometry. Cells derived from CD47^−/− mice served as a negative control in CD47 immunofluorescence labeling and measurement by flow cytometry. B, CD47 expression levels on the surfaces of platelets (PLT), neutrophils (PMN), monocytes (MO), and red blood cells (RBC), respectively. Shiga toxin-negative strain 99A041 (O157:H19) was used as a control for STEC O157:H7 (strain 99G144). Data were presented as mean±SD of three independent experiments. *, p<0.05.