<p>(A) Pelvis phenotype of P21 control and <i>Atrx<sup>Col2Cre</sup></i> mice. Arrows indicate the site of delayed ossification in mutant mice. (B) Hind limb of mutant mouse with one additional digit, before and after skeletal preparation to stain for cartilage (blue) and bone (red). The additional digit is indicated by an arrow.</p
<p>(A) Skeletons of 6-day-old control (left) and <i>Twist1<sup>flox/+</sup></i>; <i>Twist2<sup>Cre/+...
<p>Near adjacent sections from the tarsal 2-metatarsal II joint of 7-d-old mice. (A and B) LACZ stai...
Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cart...
Arsal cartilage elements (white arrow) and elongation of the digits in -/-. Note increased intensity...
encodes a chromatin remodeling protein, however the role of ATRX in skeletal development is current...
BACKGROUND:Mutations in the human ATRX gene cause developmental defects, including skeletal deformit...
<p>A) Fibrillation or fissuring of the articular surfaces was not observed in elbows of control or m...
<p>Skeleton preparations from 6-week-old <i>R26<sup>floxneoWnt4</sup>; Col2a1-Cre</i> mutants and <i...
<p>(A) Radiographs of representative <i>Trsp<sup>fl/fl</sup></i> (left) and <i>Trsp<sup>fl/fl</sup> ...
Studies of a number of mouse mutations with skeletal defects have contributed significantly to the u...
<p>MicroCT images in (A,B) WT and (C,D) homozygote VCP<sup>R155H/R155H</sup> animals. Bone images of...
<p>Chondroskeletal preparation of the HLs of E14.5 embryos (micrographs on the left) and full skelet...
<p>(A–E) Alcian blue/Alizarin red staining of (A) elbow joints (lateral view), (B) knee joints (late...
<p>(A) Micro-CT imaging of mineralized skull. Note the demineralization of the skull in the mutant m...
<p>(A–B) Body weights of males (A) or females (B) with indicated genotypes. 1: wild type; 2: <i>Osx-...
<p>(A) Skeletons of 6-day-old control (left) and <i>Twist1<sup>flox/+</sup></i>; <i>Twist2<sup>Cre/+...
<p>Near adjacent sections from the tarsal 2-metatarsal II joint of 7-d-old mice. (A and B) LACZ stai...
Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cart...
Arsal cartilage elements (white arrow) and elongation of the digits in -/-. Note increased intensity...
encodes a chromatin remodeling protein, however the role of ATRX in skeletal development is current...
BACKGROUND:Mutations in the human ATRX gene cause developmental defects, including skeletal deformit...
<p>A) Fibrillation or fissuring of the articular surfaces was not observed in elbows of control or m...
<p>Skeleton preparations from 6-week-old <i>R26<sup>floxneoWnt4</sup>; Col2a1-Cre</i> mutants and <i...
<p>(A) Radiographs of representative <i>Trsp<sup>fl/fl</sup></i> (left) and <i>Trsp<sup>fl/fl</sup> ...
Studies of a number of mouse mutations with skeletal defects have contributed significantly to the u...
<p>MicroCT images in (A,B) WT and (C,D) homozygote VCP<sup>R155H/R155H</sup> animals. Bone images of...
<p>Chondroskeletal preparation of the HLs of E14.5 embryos (micrographs on the left) and full skelet...
<p>(A–E) Alcian blue/Alizarin red staining of (A) elbow joints (lateral view), (B) knee joints (late...
<p>(A) Micro-CT imaging of mineralized skull. Note the demineralization of the skull in the mutant m...
<p>(A–B) Body weights of males (A) or females (B) with indicated genotypes. 1: wild type; 2: <i>Osx-...
<p>(A) Skeletons of 6-day-old control (left) and <i>Twist1<sup>flox/+</sup></i>; <i>Twist2<sup>Cre/+...
<p>Near adjacent sections from the tarsal 2-metatarsal II joint of 7-d-old mice. (A and B) LACZ stai...
Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cart...