<p>Concentration of PZQ is shown on the left side of the figure. The photographs show the effect of the drug on the length of the worms and the degree of recovery of the worm's length after removal from the sub-lethal concentrations of the drug. Note the difference in the response of the two isolates to the 8 µg/ml dose. The results for the PR1 strain which was also tested were similar to those shown for the KNY isolate.</p
<p>Adult worm pairs were incubated with increasing concentrations of GF109203X, or 1 µM PMA and movi...
S. mansoni couples were cultured for 72 h with 5 μM harmonine with a change of medium and compound e...
<p>The quantification of the number of tubercles was performed using three-dimensional images obtain...
<p>KCW (2008) refers to a subset of the KCW isolate kept in Kenya since 2005 that was tested in 2008...
<p>Adult parasites were perfused at 6–7 weeks post-infection and incubated overnight in schistosome ...
<p>Adult worms were incubated with the indicated compounds and phenotypes were scored as described u...
<p>Adult <i>S. mansoni</i> worm pairs were maintained in medium containing varying concentrations of...
(A) Percentage of relative motility of adult worms treated with different concentrations of GSK343 a...
<p>Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy...
<p> = 20 mice were used for each group.<sup>, </sup> p<0.05 (Non-selected vs. Selected). N</p><p><su...
The use of chemotherapy on a mass scale in endemic areas may lead to the appearance of resistant iso...
(A) Scanning electron microscopy of juvenile parasites; note that the size bar is shown within the b...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...
It has been demonstrated that continuous exposure to amodiaquine (AQ) alone elicits in vitro antisch...
<p>Representative confocal laser microscopy images of the gut of <i>S</i>. <i>mansoni</i> male worms...
<p>Adult worm pairs were incubated with increasing concentrations of GF109203X, or 1 µM PMA and movi...
S. mansoni couples were cultured for 72 h with 5 μM harmonine with a change of medium and compound e...
<p>The quantification of the number of tubercles was performed using three-dimensional images obtain...
<p>KCW (2008) refers to a subset of the KCW isolate kept in Kenya since 2005 that was tested in 2008...
<p>Adult parasites were perfused at 6–7 weeks post-infection and incubated overnight in schistosome ...
<p>Adult worms were incubated with the indicated compounds and phenotypes were scored as described u...
<p>Adult <i>S. mansoni</i> worm pairs were maintained in medium containing varying concentrations of...
(A) Percentage of relative motility of adult worms treated with different concentrations of GSK343 a...
<p>Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy...
<p> = 20 mice were used for each group.<sup>, </sup> p<0.05 (Non-selected vs. Selected). N</p><p><su...
The use of chemotherapy on a mass scale in endemic areas may lead to the appearance of resistant iso...
(A) Scanning electron microscopy of juvenile parasites; note that the size bar is shown within the b...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...
It has been demonstrated that continuous exposure to amodiaquine (AQ) alone elicits in vitro antisch...
<p>Representative confocal laser microscopy images of the gut of <i>S</i>. <i>mansoni</i> male worms...
<p>Adult worm pairs were incubated with increasing concentrations of GF109203X, or 1 µM PMA and movi...
S. mansoni couples were cultured for 72 h with 5 μM harmonine with a change of medium and compound e...
<p>The quantification of the number of tubercles was performed using three-dimensional images obtain...