<p>(A) Blood glucose levels. Diabetes (DM) induced a sharp increase in glucose levels which remained high even after viral infection with SERCA2a and β-gal transgenes. (B) LV/BW ratio calculated based on the LV weight and the final weight of the animal (prior to death). Changes in contractility (dP/dt max) (C), in relaxation (dP/dt min) (D) and in tau (E) in the different groups. All data shown as means±SD. LV, left ventricle; BW, body weight. <sup>*</sup><i>P</i><0.05 Control vs. DM; <sup>#</sup><i>P</i><0.01 DM vs. DM+SERCA; <sup>‡</sup><i>P</i><0.05 DM+β-Gal vs. DM+SERCA; ̂ <i>P</i> = 0.04 DM+SERCA vs. DM+β-Gal.</p
<p>The type of diabetes and the method of inducing diabetes significantly affect absolute heart weig...
Genetic rodent models of type 2 diabetes are routinely utilized in studies of diabetes-related cardi...
Background: Heart failure syndrome is an aspect of primary or secondary heart disease and associated...
<p>Larger decrease in %FS (B) and ï (C) in diabetic mice compared to control mice. Decrease in diast...
Diabetic cardiomyopathy entails a serious cardiac dysfunction induced by alterations in structure an...
<p>Compared with Con group, the data, including FS, CO and ±dp/dt, revealed significantly decreased ...
<p>A: LV end-systolic diameters 24 hour post -MI. The LV end-systolic diameter increased in diabetic...
<p>Left ventricle thickness (panel B) and cardiomyocyte size (panel D) were markedly increased in D2...
Background: Although clinical diabetes mellitus is obviously a high risk factor for myocardial infar...
<p>(<b>a</b>) mPET analysis demonstrated a significant increase in the mean value of the myocardial ...
<p>(A) Representative signal averaged sarcomere length measurements during contraction recorded from...
<p>Group S are untreated wild-type sham-operated mice; Group MI are untreated wild-type infarcted mi...
The contributions of changes in primary systolic and diastolic properties, limitations of contractil...
Diabetes and the often accompanying cardiovascular diseases including cardiomyopathy represent a com...
This study examined cardiac function and glucose metabolism in the 6-month-old db/db mouse, a model ...
<p>The type of diabetes and the method of inducing diabetes significantly affect absolute heart weig...
Genetic rodent models of type 2 diabetes are routinely utilized in studies of diabetes-related cardi...
Background: Heart failure syndrome is an aspect of primary or secondary heart disease and associated...
<p>Larger decrease in %FS (B) and ï (C) in diabetic mice compared to control mice. Decrease in diast...
Diabetic cardiomyopathy entails a serious cardiac dysfunction induced by alterations in structure an...
<p>Compared with Con group, the data, including FS, CO and ±dp/dt, revealed significantly decreased ...
<p>A: LV end-systolic diameters 24 hour post -MI. The LV end-systolic diameter increased in diabetic...
<p>Left ventricle thickness (panel B) and cardiomyocyte size (panel D) were markedly increased in D2...
Background: Although clinical diabetes mellitus is obviously a high risk factor for myocardial infar...
<p>(<b>a</b>) mPET analysis demonstrated a significant increase in the mean value of the myocardial ...
<p>(A) Representative signal averaged sarcomere length measurements during contraction recorded from...
<p>Group S are untreated wild-type sham-operated mice; Group MI are untreated wild-type infarcted mi...
The contributions of changes in primary systolic and diastolic properties, limitations of contractil...
Diabetes and the often accompanying cardiovascular diseases including cardiomyopathy represent a com...
This study examined cardiac function and glucose metabolism in the 6-month-old db/db mouse, a model ...
<p>The type of diabetes and the method of inducing diabetes significantly affect absolute heart weig...
Genetic rodent models of type 2 diabetes are routinely utilized in studies of diabetes-related cardi...
Background: Heart failure syndrome is an aspect of primary or secondary heart disease and associated...