<p>(A) Female Hartley guinea pigs (n = 6 for each group) were i.m. administered with the indicated doses of cAb 29, followed by s.c. challenge with 40LD<sub>50</sub> of <i>B. anthracis</i> Vollum spores 14 hrs later. (B) 30 days after the first challenge, surviving animals from groups 20 and 10+10 mg/kg were re-challenged with the same dose (40LD<sub>50</sub>), and survival was then monitored for another 14 days.</p
Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alte...
<p>Guinea pigs were inoculated with graded spore inocula of each strain by subcutaneous route in the...
<p>Survival curves of BCG vaccinated guinea pigs (triangles) and unvaccinated guinea pigs (open squa...
pigs. against Bacillus anthracis infection in guinea Passive protection by polyclonal antibodie
<p>(A) Scheme of immunization and infection. Guinea pigs were immunized IN with PIV5 or PIV5-H7 (10<...
Bacillus anthracis protective antigen (PA) has been produced from a recombinant B. subtilis and its ...
a<p>Guinea pigs were treated i.p. with a neutralizing MAb combination (2 mg 4G7+1.5 mg 1H3+1.5 mg 2G...
Nonhuman primates (NHPs) and rabbits are the animal models most commonly used to evaluate the effica...
AbstractObjectiveRecombinant protective antigen (rPA) is the active pharmaceutical ingredient of a s...
<p>Severe symptoms were based on daily monitoring until 7 days post challenge (one guinea pig of eac...
This study was concerned on the production of Bacillus anthracis toxin and its use as a vaccine. Two...
<p>Severity of symptoms was based on daily monitoring until 7 days post challenge.</p>a<p>Guinea pig...
<p>Data show the evolution of the protection given by the vaccination. Only the BCG group demonstrat...
a<p>Guinea pigs were treated i.p. with 5 mg of the MAb as shown in the table on day 1 after infectio...
<p>(A) Experimental protocol for evaluating the protective efficacy of MtbΔ<i>mms</i> against <i>M.t...
Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alte...
<p>Guinea pigs were inoculated with graded spore inocula of each strain by subcutaneous route in the...
<p>Survival curves of BCG vaccinated guinea pigs (triangles) and unvaccinated guinea pigs (open squa...
pigs. against Bacillus anthracis infection in guinea Passive protection by polyclonal antibodie
<p>(A) Scheme of immunization and infection. Guinea pigs were immunized IN with PIV5 or PIV5-H7 (10<...
Bacillus anthracis protective antigen (PA) has been produced from a recombinant B. subtilis and its ...
a<p>Guinea pigs were treated i.p. with a neutralizing MAb combination (2 mg 4G7+1.5 mg 1H3+1.5 mg 2G...
Nonhuman primates (NHPs) and rabbits are the animal models most commonly used to evaluate the effica...
AbstractObjectiveRecombinant protective antigen (rPA) is the active pharmaceutical ingredient of a s...
<p>Severe symptoms were based on daily monitoring until 7 days post challenge (one guinea pig of eac...
This study was concerned on the production of Bacillus anthracis toxin and its use as a vaccine. Two...
<p>Severity of symptoms was based on daily monitoring until 7 days post challenge.</p>a<p>Guinea pig...
<p>Data show the evolution of the protection given by the vaccination. Only the BCG group demonstrat...
a<p>Guinea pigs were treated i.p. with 5 mg of the MAb as shown in the table on day 1 after infectio...
<p>(A) Experimental protocol for evaluating the protective efficacy of MtbΔ<i>mms</i> against <i>M.t...
Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alte...
<p>Guinea pigs were inoculated with graded spore inocula of each strain by subcutaneous route in the...
<p>Survival curves of BCG vaccinated guinea pigs (triangles) and unvaccinated guinea pigs (open squa...