<i>P. aeruginosa</i> Δ<i>mutS</i> and Δ<i>mutL</i> strains exhibit enhanced microcolony initiation and development (A), and also show increased total biofilm volume (B) and maximum microcolony thickness (C).

<p>Biofilm development of <i>P. aeruginosa</i> PAO1 WT, Δ<i>mutS</i>, Δ<i>mutL</i>, Δ<i>mutS</i>+pUCPMS and Δ<i>mutL</i>+pUCmutL grown in continuous culture flow cells over a 10 day period and examined using confocal scanning laser microscopy. Asterisks indicate a significant difference compared with WT or related complemented strain (P<0.05).