Over-expression of BAD increases tumor growth rate and tumor take.

<p>Nude mice received four subcutaneous injections of 2×10⁶ C4-2Luc or C4-2LucBAD cells. A) Representative whole body images of the animals obtained at 1 day and 2 weeks after implantations using the IVIS100 and Living Image® software (Xenogen). B) Dot plot showing fold increase and median luminescence in mice injected with C4-2Luc and C4-2LucBAD cells. C) Percent of palpable tumors (over 5 mm) developed at injection sites. D) Representative tissue sections of formalin-fixed tumors stained for proliferation marker Ki67.