<p>A. Representative examples of WT (left panel) and <i>Il10<sup>−/−</sup></i> colons (middle and right panels) from AOM-treated mice 16 weeks after transfer to SPF conditions. B. Tumor penetrance and multiplicity in WT and <i>Il10<sup>−/−</sup></i> mice (left and right panels) (p = 0.034). C. WT and <i>Il10<sup>−/−</sup></i> colon inflammation scores, distal colon <i>Il12p40</i> and <i>Tnfα</i> mRNA levels after 18–20 weeks under SPF conditions (p = 0.026).</p
<p>Mice were treated with DSS or the DSS/<i>Candida</i> combination as described in the legend of <a...
<p>(A) Endoscopic images of inflamed mucosa and tumor of AOM/DSS-colitis as well as the IL10<sup>−/−...
<p>IL-10<sup>wt/wt</sup>; NF-κB<sup>EGFP</sup> and IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> were as...
<p>A. Representative histology observed in <i>Il10<sup>−/−</sup></i> and <i>Il10<sup>−/−</sup></i>; ...
<p>A significant increase in IL-17 (A), IL-1β (c), TNFα (D), IL-12 (E) and IL-13 (F) was seen in the...
<p>(A and B) Relative mRNA expressions for IL-1β, IL-6, MIP-2 (A), IFN-γ and TNF (B) in colonic muco...
<p>(A) Immunohistochemistry stainings of colon sections from WT mice using anti-IL-17F and IL-17A an...
<p>Gnotobiotic IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> mice were associated with <i>C. jejuni</i> ...
<p>Gene expression in colon of IL-10<sup>−/−</sup> and GC-C<sup>−/−</sup>IL-10<sup>−/−</sup> mice ar...
*<p>p<0.05 compared compared with colons from WT control, WT PM<sub>10</sub>, and IL-10<sup>−/−</sup...
<p>A) Relative expression of IL-6 in the inflammatory infiltrates of the colon mucosa at days 7, 14 ...
<p>(<b>A</b>) Schematic overview of the colon carcinogenesis model. (<b>B</b>) Macroscopic changes i...
<p>(<b>A</b>) Representative HE-staining images of rectal tissues from OPN KO mice at 4, 8, and 12 w...
A Spleen weights (mean ± SE) of non-tumor mice (n = 12) and tumor-bearing mice (n = 10) after 24 day...
<p>(A) Histopathology (H&E) of colonic tumor disease induced by CAC protocol (n≥9/ genotype). Repres...
<p>Mice were treated with DSS or the DSS/<i>Candida</i> combination as described in the legend of <a...
<p>(A) Endoscopic images of inflamed mucosa and tumor of AOM/DSS-colitis as well as the IL10<sup>−/−...
<p>IL-10<sup>wt/wt</sup>; NF-κB<sup>EGFP</sup> and IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> were as...
<p>A. Representative histology observed in <i>Il10<sup>−/−</sup></i> and <i>Il10<sup>−/−</sup></i>; ...
<p>A significant increase in IL-17 (A), IL-1β (c), TNFα (D), IL-12 (E) and IL-13 (F) was seen in the...
<p>(A and B) Relative mRNA expressions for IL-1β, IL-6, MIP-2 (A), IFN-γ and TNF (B) in colonic muco...
<p>(A) Immunohistochemistry stainings of colon sections from WT mice using anti-IL-17F and IL-17A an...
<p>Gnotobiotic IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> mice were associated with <i>C. jejuni</i> ...
<p>Gene expression in colon of IL-10<sup>−/−</sup> and GC-C<sup>−/−</sup>IL-10<sup>−/−</sup> mice ar...
*<p>p<0.05 compared compared with colons from WT control, WT PM<sub>10</sub>, and IL-10<sup>−/−</sup...
<p>A) Relative expression of IL-6 in the inflammatory infiltrates of the colon mucosa at days 7, 14 ...
<p>(<b>A</b>) Schematic overview of the colon carcinogenesis model. (<b>B</b>) Macroscopic changes i...
<p>(<b>A</b>) Representative HE-staining images of rectal tissues from OPN KO mice at 4, 8, and 12 w...
A Spleen weights (mean ± SE) of non-tumor mice (n = 12) and tumor-bearing mice (n = 10) after 24 day...
<p>(A) Histopathology (H&E) of colonic tumor disease induced by CAC protocol (n≥9/ genotype). Repres...
<p>Mice were treated with DSS or the DSS/<i>Candida</i> combination as described in the legend of <a...
<p>(A) Endoscopic images of inflamed mucosa and tumor of AOM/DSS-colitis as well as the IL10<sup>−/−...
<p>IL-10<sup>wt/wt</sup>; NF-κB<sup>EGFP</sup> and IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> were as...