Effect of different intraluminal treatments on substance P (SP)-induced histological changes.

<p>A) Bladder inflammation scores across all treatment groups (intraluminal treatment for each group is in parenthesis). Substance P produced bladder edema and inflammation when compared to the control group. Groups treated with CD74 ab (CD74) and/or GRP78 ab (GRP) had bladder scores that were not significantly different from control. B–G. Representative H&E stained bladder sections from each group. * = comparison to saline p<0.05; *** = p<0.001; (#) = comparison to SP(Sal) p<0.05;(###) = p<0.001; n.s. = not significant.