a<p>Competitive Index, determined by dividing the ratio of wild-type to mutant at 48 hpi by the ratio present in the inoculum. Significant CI>1 indicates mutant has a fitness defect.</p>b<p><i>P</i>-values determined by Wilcoxon matched pairs test. Significant <i>P</i>-values are bolded.</p
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p>C57/BL6 mice were infected i.p. with equal numbers of mutant and wild type bacteria (each 5×10<su...
(A and B) Relationship between the competitive index of mutants in colonies (A) or stationary phase ...
<p>Fitness (mean ± SD; <i>n</i> = 4) of antibiotic-resistant mutants generated by <i>ΔmutY</i> (circ...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p><i>P</i> values are shown in parentheses. The range of TraDIS fitness scores obtained in the chic...
1<p>(wild-type output/mutant output)/(wild-type input/mutant input).</p>2<p>Paired t test.</p>*<p>Va...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p><b>A</b>. Estimated fitness costs (normalized by setting fitness cost of wild type to 0), <b>B</b...
<p>The Δ4904 single mutant was outcompeted by the wild type. <b>Panels A, B</b> and <b>C</b> depict ...
<p>Regions where mutations have recessive effects (0< <i>h</i><0.5) are shown in gray and additive e...
<p>Mice were challenged with the sRNA mutants and parental TIGR4 in a competitive index model of inf...
<p>CBA/J mice were transurethrally inoculated with 1x10<sup>5</sup> CFU of a 1:1 mixture of wild-typ...
<p>(A) <i>In vitro</i> competition studies of the various mutants and their complemented strains in ...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p>C57/BL6 mice were infected i.p. with equal numbers of mutant and wild type bacteria (each 5×10<su...
(A and B) Relationship between the competitive index of mutants in colonies (A) or stationary phase ...
<p>Fitness (mean ± SD; <i>n</i> = 4) of antibiotic-resistant mutants generated by <i>ΔmutY</i> (circ...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p><i>P</i> values are shown in parentheses. The range of TraDIS fitness scores obtained in the chic...
1<p>(wild-type output/mutant output)/(wild-type input/mutant input).</p>2<p>Paired t test.</p>*<p>Va...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p><b>A</b>. Estimated fitness costs (normalized by setting fitness cost of wild type to 0), <b>B</b...
<p>The Δ4904 single mutant was outcompeted by the wild type. <b>Panels A, B</b> and <b>C</b> depict ...
<p>Regions where mutations have recessive effects (0< <i>h</i><0.5) are shown in gray and additive e...
<p>Mice were challenged with the sRNA mutants and parental TIGR4 in a competitive index model of inf...
<p>CBA/J mice were transurethrally inoculated with 1x10<sup>5</sup> CFU of a 1:1 mixture of wild-typ...
<p>(A) <i>In vitro</i> competition studies of the various mutants and their complemented strains in ...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
CBA/J mice were inoculated via the tail vein with 1x107 CFU of a 1:1 mixture of wild-type P. mirabil...
<p>C57/BL6 mice were infected i.p. with equal numbers of mutant and wild type bacteria (each 5×10<su...
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