<p>INS-1E cells were treated with DEDTC at 5 mM glucose. A) Insulin gene expression normalized to Cltc, HPRT and HSPcb. Data are mean and SEM (*p<0.01). N = 6. B) Insulin secretion related to insulin content in INS-1E cells. Data are mean and SEM (*p<0.01). N = 3.</p
<p>INS-1 cells were treated with NG, 1% GS, 2% GS, 5% GS or 10% GS for 1, 3, 6 and 12 h, and then <i...
<p>(a) Expression of insulin receptor isoforms A and B; (b) transcript levels of insulin signaling p...
<p>(A) Insulin secretion of INS-1E cells was measured at different times of 20 mM glucose stimulatio...
<p>INS-1E cells were treated with DEDTC at 5 mM glucose. A) ZnT-3 gene expression normalised to Cltc...
<p>INS 832/13 cells were transfected with ScrAB, siIDHc#1 or siIDHc#2. A, IDHc mRNA expression level...
<p>Seventy two hours post transfection cells were stimulated with basal (3 mM) or high (25 mM) gluco...
<p>INS-1E cells were exposed for 3 days to different culture conditions: 5.6 mM glucose (G5.6), 25 m...
<p>Basal (1 mM glucose) and glucose-stimulated (20 mM glucose) insulin secretion in EndoC-βH1 (A) an...
<p>Results represent deoxyglucose uptake by 3T3-L1 cells before and after insulin stimulation (50 nM...
<p>(A) Real-time PCR analysis was performed to measure Insulin1 and Insulin2 mRNA 24 h after treatme...
<p>(A) Cellular insulin content was examined after MIN6 cells were incubated in normoxia (20% O<sub>...
<p>Min 6 cells were transiently infected with EV, CIP, p25, p25/CIP, and p25/DNcdk5 constructs respe...
<p>Results are reported as % recovery of total cellular insulin content relative to untreated contro...
<p>Insulin content of Pr-LP, Pr-HP, C4-LP, and C4-HP MIN6 cells (A). The insulin content of Pr-HP ce...
<p>(A) Effect of C8 and DSC108 on insulin secretion from MIN6-K8 cells. Cells were stimulated by eac...
<p>INS-1 cells were treated with NG, 1% GS, 2% GS, 5% GS or 10% GS for 1, 3, 6 and 12 h, and then <i...
<p>(a) Expression of insulin receptor isoforms A and B; (b) transcript levels of insulin signaling p...
<p>(A) Insulin secretion of INS-1E cells was measured at different times of 20 mM glucose stimulatio...
<p>INS-1E cells were treated with DEDTC at 5 mM glucose. A) ZnT-3 gene expression normalised to Cltc...
<p>INS 832/13 cells were transfected with ScrAB, siIDHc#1 or siIDHc#2. A, IDHc mRNA expression level...
<p>Seventy two hours post transfection cells were stimulated with basal (3 mM) or high (25 mM) gluco...
<p>INS-1E cells were exposed for 3 days to different culture conditions: 5.6 mM glucose (G5.6), 25 m...
<p>Basal (1 mM glucose) and glucose-stimulated (20 mM glucose) insulin secretion in EndoC-βH1 (A) an...
<p>Results represent deoxyglucose uptake by 3T3-L1 cells before and after insulin stimulation (50 nM...
<p>(A) Real-time PCR analysis was performed to measure Insulin1 and Insulin2 mRNA 24 h after treatme...
<p>(A) Cellular insulin content was examined after MIN6 cells were incubated in normoxia (20% O<sub>...
<p>Min 6 cells were transiently infected with EV, CIP, p25, p25/CIP, and p25/DNcdk5 constructs respe...
<p>Results are reported as % recovery of total cellular insulin content relative to untreated contro...
<p>Insulin content of Pr-LP, Pr-HP, C4-LP, and C4-HP MIN6 cells (A). The insulin content of Pr-HP ce...
<p>(A) Effect of C8 and DSC108 on insulin secretion from MIN6-K8 cells. Cells were stimulated by eac...
<p>INS-1 cells were treated with NG, 1% GS, 2% GS, 5% GS or 10% GS for 1, 3, 6 and 12 h, and then <i...
<p>(a) Expression of insulin receptor isoforms A and B; (b) transcript levels of insulin signaling p...
<p>(A) Insulin secretion of INS-1E cells was measured at different times of 20 mM glucose stimulatio...