Human NS cell cultures harbour slow-cycling or dormant cells.

<p>Approximately 5% of human NS cells remained viable after 5 days exposure to the antimitotic drug Ara-c. The viable cells retained Nestin and Sox2 expression but did not express Ki67 or CD133 (A, B). When these cells were re-plated into medium without Ara-c for 10 days, approximately 14.6% of cells expressed Ki67 and 8.7% expressed CD133 (C, D). Yellow arrows in (C) indicate Ki67 positive cells.