Circulating mature B cells in FcRγ deficient and Bcl2-transgenic mice following anti BAFF-R 9B9 injection.

<p>Panel A. FcRγ^−/− mice were injected at day 0 and the percentage of CD93⁻CD19⁺ mature B cells in the blood was determined at day 14 by FACS analysis. Non-injected FcRγ^−/− mice were used as controls. The difference between FcRγ^−/− treated versus untreated mice was statistically significant (p<0.05). Panel B. The percentage of mature B cells in the blood of C57BL/6 and Bcl2 transgenic mice at day 14 following the injection of 9B9 mAb. The difference between C57BL/6 and Bcl2 transgenic mice following 9B9 treatment was statistically significant (p<0.01).