Survival of BALB/c mice immunized and depleted/undepleted of CD8⁺ T-cells.

<p>BALB/c mice were immunized with J8-DT/DT or PBS parenterally. For <i>in vivo</i> depletion of CD8⁺ T-cells mice were administered with 1 mg of anti-CD8 (α-CD8-beta clone 53.5.8) mAb intraperitoneally over a set time-course before and after GAS challenge. Survival in J8-DT immunized and CD8⁺ T-cell depleted/undepleted BALB/c mice are shown. The abbreviation D stands for immunized/depleted mice whereas U/D represents immunized/undepleted. Significance is represented as * p<0.05 and ** p<0.01.