Kinetics of ERK1/2, p38, RAC1 and RAS activation in LNCaP cells following cross-linking of anti-PSMA, anti-VCAM-1 or 7E11c mAb^a).

a)<p>The 7E11c mAb recognizes an intracellular PSMA epitope and is therefore used as a further control of the experiment described.</p>b)<p>Results of gel densitometry are expressed as the ratio±SEM of activated/total protein as evaluated by measuring the respective areas.</p>c)<p>Statistical significance is reported with respect to the “No treatment” data.</p>d)<p>ns = not significant.</p>e)<p>nd = not determined.