<p>Baseline heart rates of test/subject mice were calculated from a 90-s period that occurred immediately before the beginning of each habituation, conditioning/pre-exposure and testing period. Each of these periods began 20 min after a mouse was placed in the conditioning apparatus. There were no within-strain differences in baseline heart rate across different phases of the conditioning protocol. A previously described strain difference in baseline heart rate <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004387#pone.0004387-Depino1" target="_blank">[42]</a> was found during all phases of the experiments (P<0.01). Data are presented as the mean±s.e.m.</p
<p>(A) Instant HR responses of the same mouse during three recall trials, trial#1, trial#5 and trial...
Graphical plots of beat-by-beat heart rate (HR) patterns, e.g., Poincaré plots, provide information ...
<p>Data are presented as the mean ± SEM (error bar). WT & CD88-/- mice; bpm, beats per minutes; hr, ...
<p>HR was measured during (a) the first and second conditioning session in mice that directly receiv...
<p>During habituation to the conditioning apparatus, HR was measured for 5 min following presentatio...
<p>(A) Bars show the mean heart rate (n = 50 trials) on the second day of habituation for the wild-t...
<p>HR was measured during (a) the first and second conditioning session in subjects that experienced...
<p>Note that all interventions decreased to the same extent the baseline HR of KO mice, which became...
When tested on the treadmill mice do not display a graded increase of heart rate (HR), but rather a ...
<p>The basal heart rate, mean arterial pressure (MAP) and pulse pressure of mice prenatally exposed ...
<p>(A) Instant HR responses of an individual mouse during three recall trials, trial#1, trial#5 and ...
<p>(A) Illustration of a fear conditioning chamber for producing a tone-shock pairing fear memory. (...
The concept of refinement is one of the major issues in the field of laboratory animal science and a...
Many studies have shown that housing mice individually over a long period significantly alters their...
<p>Statistical differences in heart rate across time for either the CS or US were determined by one-...
<p>(A) Instant HR responses of the same mouse during three recall trials, trial#1, trial#5 and trial...
Graphical plots of beat-by-beat heart rate (HR) patterns, e.g., Poincaré plots, provide information ...
<p>Data are presented as the mean ± SEM (error bar). WT & CD88-/- mice; bpm, beats per minutes; hr, ...
<p>HR was measured during (a) the first and second conditioning session in mice that directly receiv...
<p>During habituation to the conditioning apparatus, HR was measured for 5 min following presentatio...
<p>(A) Bars show the mean heart rate (n = 50 trials) on the second day of habituation for the wild-t...
<p>HR was measured during (a) the first and second conditioning session in subjects that experienced...
<p>Note that all interventions decreased to the same extent the baseline HR of KO mice, which became...
When tested on the treadmill mice do not display a graded increase of heart rate (HR), but rather a ...
<p>The basal heart rate, mean arterial pressure (MAP) and pulse pressure of mice prenatally exposed ...
<p>(A) Instant HR responses of an individual mouse during three recall trials, trial#1, trial#5 and ...
<p>(A) Illustration of a fear conditioning chamber for producing a tone-shock pairing fear memory. (...
The concept of refinement is one of the major issues in the field of laboratory animal science and a...
Many studies have shown that housing mice individually over a long period significantly alters their...
<p>Statistical differences in heart rate across time for either the CS or US were determined by one-...
<p>(A) Instant HR responses of the same mouse during three recall trials, trial#1, trial#5 and trial...
Graphical plots of beat-by-beat heart rate (HR) patterns, e.g., Poincaré plots, provide information ...
<p>Data are presented as the mean ± SEM (error bar). WT & CD88-/- mice; bpm, beats per minutes; hr, ...