Single marker Transmission Disequilibrium Test (TDT) of association with severe malaria in Gambian, Kenyan and Malawian child-parental trios.
- Valentina D. Mangano (374987)
- Taane G. Clark (106263)
- Sarah Auburn (106239)
- Susana Campino (56411)
- Mahamadou Diakite (22543)
- Andrew E. Fry (250890)
- Angela Green (250894)
- Anna Richardson (1706)
- Muminatou Jallow (35062)
- Fatou Sisay-Joof (130771)
- Margaret Pinder (1712)
- Michael J. Griffiths (251397)
- Charles Newton (229111)
- Norbert Peshu (40511)
- Thomas N. Williams (34879)
- Kevin Marsh (9406)
- Malcolm E. Molyneux (52383)
- Terrie E. Taylor (141718)
- David Modiano (34881)
- Dominic P. Kwiatkowski (106264)
- Kirk A. Rockett (138127)
Publication date
February 2013
DOIAbstract
<p>The table shows the SNPs tested in association analysis with severe malaria and results of the TDT in the three populations of affected child-parental trios. Inform is the number of informative trios. OR: Odds Ratio comparing the risk of the minor vs major allele. LCL and UCL: Lower and Upper Confidence Limits of a 95% Confidence Interval respectively. TDT P: P-value for the family-based test of association. P-values<0.05 are shown in bold.</p
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