The contribution of lysozyme from neutrophils to survival and colonization of mutants lacking peptidoglycan modifications.

<p>A) Neutrophils isolated from human blood were incubated with serum opsonized bacteria and survival was assessed following a 45 min incubation. Percent survival was calculated based on viable counts (CFU/ml) relative to no neutrophil controls. (^*** p<0.001). B) Neutrophils were depleted with anti-Ly6G antibody RB6-8C5 prior to challenge with an equal inoculum of <i>pgdAadr</i> and wild-type (WT) strains. Controls received rat IgG. Two days post-inoculation nasal lavages were obtained to quantify the competitive index. (^** p<0.01).