<p>A. A schematic of the overlapping EBox/GATA (GATA/EBoxwt) binding sites at −495 and −486 base pairs within the PGC-1α promoter is shown. Mutations to the GATA/EBoxwt oligonucleotide that were introduced by nucleotide exchange to abolish GATA (GATAmt) or EBox (EBoxmt) binding are bolded. B. Representative EMSAs of Vehicle- (−) and AICAR− (+) treated nuclear extracts incubated with GATAmt or EBoxmt radiolabeled probes in the presence or absence of USF-1 Antibody. FP: free probe, 25× CO, and 50CO: 25-fold and 50-fold molar excess of cold oligonucleotide, No Ab: No Antibody, USF-1: USF-1 antibody. C. Relative luciferase activity of the PGC-1α promoter constructs in vehicle- or AICAR-treated cells is shown. Values are means±S.E.M, * p<0.05 ve...
<p><b>A.</b> Diagram of the promoter region of <i>STM2209-STM2208</i>, showing GATC sites (red squar...
<p>Wt proximal γ-globin promoter probe with nuclear extracts from human fetal liver, K562 cells and ...
<p><b>A.</b> Binding of <i>MYCT1-TV</i> E-box sites to c-Myc in vitro detected by EMSAs. The symbol ...
<p>A. Representative EMSAs of nuclear extracts from Vehicle− (−AIC) and AICAR− (+AIC) treated cells ...
<p>(<b>A</b>) Alignment of the nucleotide sequence of proximal region of human (top line) and mouse ...
<p>(A) The enhancer activities of the constructs, which included <i>GATA-2</i> upstream or intron re...
The mechanisms by which PGC-1alpha gene expression is controlled in skeletal muscle remains largely ...
<p>A. Representative western blots of protein extracts made from C<sub>2</sub>C<sub>12</sub> cells t...
<p>(<b>A</b>) Schematic diagram of the 11 GATA sites (G1–G11) in the <i>ZNF268</i> promoter. (<b>B</...
<p>Ets and GATA binding sites are indicated with a circle and square, respectively. Mutated sites ar...
AbstractTo study the regulatory mechanism of gp91phox gene expression in eosinophils, we transiently...
<p>(A) A schematic representation of GATA-REs (Wt) and their mutants (M1, M2 and M3 for CAT assay; m...
<p><b>Copyright information:</b></p><p>Taken from "Analysis of the CCR3 promoter reveals a regulator...
<p>(A) EMSA was performed by using biotinylated <i>ckβ</i>-Ets/GATA probes with or without mutations...
<p>(A) Nucleotide sequence of the three wild-type GC-box oligonucleotides probes are shown with unde...
<p><b>A.</b> Diagram of the promoter region of <i>STM2209-STM2208</i>, showing GATC sites (red squar...
<p>Wt proximal γ-globin promoter probe with nuclear extracts from human fetal liver, K562 cells and ...
<p><b>A.</b> Binding of <i>MYCT1-TV</i> E-box sites to c-Myc in vitro detected by EMSAs. The symbol ...
<p>A. Representative EMSAs of nuclear extracts from Vehicle− (−AIC) and AICAR− (+AIC) treated cells ...
<p>(<b>A</b>) Alignment of the nucleotide sequence of proximal region of human (top line) and mouse ...
<p>(A) The enhancer activities of the constructs, which included <i>GATA-2</i> upstream or intron re...
The mechanisms by which PGC-1alpha gene expression is controlled in skeletal muscle remains largely ...
<p>A. Representative western blots of protein extracts made from C<sub>2</sub>C<sub>12</sub> cells t...
<p>(<b>A</b>) Schematic diagram of the 11 GATA sites (G1–G11) in the <i>ZNF268</i> promoter. (<b>B</...
<p>Ets and GATA binding sites are indicated with a circle and square, respectively. Mutated sites ar...
AbstractTo study the regulatory mechanism of gp91phox gene expression in eosinophils, we transiently...
<p>(A) A schematic representation of GATA-REs (Wt) and their mutants (M1, M2 and M3 for CAT assay; m...
<p><b>Copyright information:</b></p><p>Taken from "Analysis of the CCR3 promoter reveals a regulator...
<p>(A) EMSA was performed by using biotinylated <i>ckβ</i>-Ets/GATA probes with or without mutations...
<p>(A) Nucleotide sequence of the three wild-type GC-box oligonucleotides probes are shown with unde...
<p><b>A.</b> Diagram of the promoter region of <i>STM2209-STM2208</i>, showing GATC sites (red squar...
<p>Wt proximal γ-globin promoter probe with nuclear extracts from human fetal liver, K562 cells and ...
<p><b>A.</b> Binding of <i>MYCT1-TV</i> E-box sites to c-Myc in vitro detected by EMSAs. The symbol ...