Electrophysiological properties of WT, PG6, and PA6 channels and their regulation by β2a and β3.

<p>The values of V₅₀ and k were calculated for each cell, then averaged. R values determined from test pulses to +20 mV. Data shown are mean±SEM from the number of cells shown in parentheses. Statistical significance of the β2a and β3 effects relative to either α₁ alone (+α₂δ1) were determined using ANOVA.</p>†<p>Currents from PG6 were completely inactivated by 350 ms, so the residual current at 25 ms (divided by peak) is reported (R₂₅).</p>§<p>Current density was estimated from the peak of the <i>I–V</i> curve, and statistical significance was determined using Student's <i>t</i>-test.</p><p>*P<0.05, **P<0.01.