<p>Serum samples were collected after a 6 hr food withdrawal from mice from the indicated chimeric groups at 8 and 24 weeks of age. Triglycerides were measured from <i>WT</i> (A) and <i>Jnk1<sup>−/−</sup></i> recipients (B) transplanted with either <i>WT</i> or <i>Jnk1<sup>−/−</sup></i> bone marrow. Serum insulin (C) and blood glucose (D) levels were measured in the <i>WT</i> recipient groups. Serum insulin (E) and blood glucose (F) levels measured in the <i>Jnk1<sup>−/−</sup></i> recipient groups. Serum resistin (G), leptin (H), and adiponectin (I) levels measured in the <i>WT</i> and <i>Jnk1<sup>−/−</sup></i> recipient groups at 24 weeks of age. Data are expressed as mean ± s.e.m. Asterisk indicates statistical significance (<i>p</i><0.05...
<p>Values are means ± SEM. The number of animals (all males) in each group is shown in parentheses.<...
<p>n = 8–13. * = p<0.05, t-test vs wild-type littermates of βIKK mice, n = 12–13.</p
<p>A 22-gauge needle was used for injection of the syngeneic islets into the bone marrow of C57BL/6 ...
<p>Glucose (GTT) and insulin (ITT) tolerance tests were performed on mice at age 22 and 26 weeks, re...
<p>Total adipose tissue JNK kinase activity (A) and insulin-stimulated insulin receptor phosphorylat...
<p>Photomicrographs of adipose tissue sections were generated after staining with hematoxylin/eosin ...
<p>A, B. Circulating insulin concentration was measured in blood samples from all genotypes at 4 mon...
<p>Cholesterol (A) and Triglyceride (B) levels measured before the start of HC diet (0 weeks of diet...
<p>(A) Plasma leptin protein levels in the fed state after 2 and 24 weeks of HFD feeding in female w...
<p>Circulating levels of leptin and insulin were measured in 6-month old female mice from the second...
<p>NIT-1 or NIT–hAAT cells were transplanted into diabetic mice. After transplantation, the blood su...
<p>(<b>A</b>) Plasma insulin was measured in each genotype fed the NCD (n = 9–10) or HFD (n = 10–15)...
<p>Serum cholesterol levels were measured in LDLr<sup>−/−</sup> at 8 and 18 weeks after transplantat...
<p>Plasma glucose (a), free fatty acids (b), insulin (c), adiponectin (d) and leptin (e) levels. Dat...
<p>(A) Glucose tolerance tests of control (white bar) and JNK<sup>SM-C</sup> (grey bar) mice when fe...
<p>Values are means ± SEM. The number of animals (all males) in each group is shown in parentheses.<...
<p>n = 8–13. * = p<0.05, t-test vs wild-type littermates of βIKK mice, n = 12–13.</p
<p>A 22-gauge needle was used for injection of the syngeneic islets into the bone marrow of C57BL/6 ...
<p>Glucose (GTT) and insulin (ITT) tolerance tests were performed on mice at age 22 and 26 weeks, re...
<p>Total adipose tissue JNK kinase activity (A) and insulin-stimulated insulin receptor phosphorylat...
<p>Photomicrographs of adipose tissue sections were generated after staining with hematoxylin/eosin ...
<p>A, B. Circulating insulin concentration was measured in blood samples from all genotypes at 4 mon...
<p>Cholesterol (A) and Triglyceride (B) levels measured before the start of HC diet (0 weeks of diet...
<p>(A) Plasma leptin protein levels in the fed state after 2 and 24 weeks of HFD feeding in female w...
<p>Circulating levels of leptin and insulin were measured in 6-month old female mice from the second...
<p>NIT-1 or NIT–hAAT cells were transplanted into diabetic mice. After transplantation, the blood su...
<p>(<b>A</b>) Plasma insulin was measured in each genotype fed the NCD (n = 9–10) or HFD (n = 10–15)...
<p>Serum cholesterol levels were measured in LDLr<sup>−/−</sup> at 8 and 18 weeks after transplantat...
<p>Plasma glucose (a), free fatty acids (b), insulin (c), adiponectin (d) and leptin (e) levels. Dat...
<p>(A) Glucose tolerance tests of control (white bar) and JNK<sup>SM-C</sup> (grey bar) mice when fe...
<p>Values are means ± SEM. The number of animals (all males) in each group is shown in parentheses.<...
<p>n = 8–13. * = p<0.05, t-test vs wild-type littermates of βIKK mice, n = 12–13.</p
<p>A 22-gauge needle was used for injection of the syngeneic islets into the bone marrow of C57BL/6 ...