OSM-11 Is Required for Normal Development

<p>(A) Thirty-one percent of <i>osm-11(lf)</i> adult animals had overtly normal vulva and did not retain eggs resembling control animals. (B) Fifty-seven percent of <i>osm-11(lf)</i> animals inappropriately retained eggs and/or had a single misshapen or protruding vulva (15% and 42%, respectively). (C) Twelve percent of <i>osm-11(lf)</i> animals had an extra protrusion near the normally positioned vulva. (D) <i>osm-11(lf)</i> animals had defects in head morphology at low frequency (arrowhead). (E) Two thirds of <i>osm-11(lf)</i> animals had a ventral protrusion behind the anus (arrowhead). <i>n</i> > 100 animals were scored.