Stochastic evolutionary simulation in the 12-mer fitness landscape.

<p>(A) The phenotype abundance of the target strongly affects the success of adaptation (<i>r</i> = 0.76, <i>P</i> = 2.2×10⁻⁴). (B) The phenotype abundance at the start of the simulation has no effect on the evolutionary outcome (<i>r</i> = −0.023, <i>P</i> = 0.17). We simulated adaptation over one million generations with a genomic mutation rate of <i>U</i> = 0.0003 and a constant population size of N = 1000.