Kaplan-Meier survival curve in mice challenged with (a) H1N1 influenza (A/PR/8/34) and (b) H5N1 influenza (A/Vietnam/1203/04).

Protection against a highly pathogenic avian influenza virus H5N1 infection.

Qiang Zou (172269)
Yanxin Hu (172273)
Jia Xue (133314)
Xiaoxu Fan (172276)
Yi Jin (38575)
Xianghua Shi (172279)
Di Meng (172282)
Xianzheng Wang (172286)
Congcong Feng (172289)
Xiaoping Xie (172293)
Yizhi Zhang (172297)
Youmin Kang (172302)
Xiaoxuan Liang (172307)
Bing Wu (172312)
Ming Wang (172316)
Bin Wang (30851)

April 2012

Mice were challenged one month after vaccination (0.5 µg PZQ/0.1 µg antigen). (A) Viral loads in ...

Csf2−/− mice succumb to influenza virus infection despite intact antiviral T and B cell responses.

Christoph Schneider (413360)
Samuel P. Nobs (546911)
Alex K. Heer (546912)
Michael Kurrer (224262)
Glynis Klinke (546913)
Nico van Rooijen (4110211)
Johannes Vogel (515351)
Manfred Kopf (224264)

April 2014

(A–I) Indicated groups of mice were infected i.t. with PR8 influenza virus (50 pfu unless otherwi...

Survival of Mice Immunized with a Single Dose of H5N1 ca Vaccine Candidates Following Lethal Challenge with H5N1 1997 wt or H5N1 2004 wt Viruses

Amorsolo L Suguitan Jr. (274800)
Josephine McAuliffe (65599)
Kimberly L Mills (65600)
Hong Jin (65601)
Greg Duke (65602)
Bin Lu (65603)
Catherine J Luke (65604)
Brian Murphy (65605)
David E Swayne (65606)
George Kemble (65607)
Kanta Subbarao (65608)

February 2013

Groups of eight mice that received a single dose of 106 TCID50 of the H5N1 ...

Results following an H5N1 challenge of immunized mice.

Dominick J. Laddy (49838)
Jian Yan (49839)
Michele Kutzler (49840)
Darwyn Kobasa (18296)
Gary P. Kobinger (49841)
Amir S. Khan (49842)
Jack Greenhouse (49843)
Niranjan Y. Sardesai (49844)
Ruxandra Draghia-Akli (49845)
David B. Weiner (49846)

February 2013

Mice were challenged with 100LD50 of an H5N1 virus (A/Hanoi/05/2005). (a) Kaplan-Meier...

Serum from humans immunized with seasonal influenza vaccine protects mice against vaccine homologous H1 and heterosubtypic H5 influenza challenge.

Ramon Roozendaal (606433)
Jeroen Tolboom (606434)
Anna Roos (113323)
Sarra Riahi (606435)
Jessica Theeuwsen (606436)
Miriam V. Bujny (469450)
Vincent Klaren (495728)
Hans J. W. M. Korse (495730)
Liesbeth Dekking (235102)
Arijan Grootenhuis (606437)
Gerrit Jan Weverling (113348)
Wouter Koudstaal (367348)
Jaap Goudsmit (17932)
Katarina Radošević (113341)

July 2014

Kaplan-Meier survival curves (left), mean bodyweight change (middle) and median clinical score (r...

Dose-dependent protection against disease symptoms and death in H7N9-challenged DBA/2J mice immunized with whole-virus H7N9 vaccine.

Walter Wodal (362628)
Michael G. Schwendinger (486392)
Helga Savidis-Dacho (346034)
Brian A. Crowe (344547)
Christine Hohenadl (696217)
Richard Fritz (64050)
Peter Brühl (366856)
Daniel Portsmouth (346035)
Anita Karner-Pichl (696218)
Dalida Balta (696219)
Leopold Grillberger (366851)
Otfried Kistner (132940)
P. Noel Barrett (344551)
M. Keith Howard (346032)

February 2015

(A) Kaplan-Meier survival curves, (B) Severity and duration of disease symptoms</p

CD4+ and CD8+ T cells both contribute to H5N1 protection.

Freek Cox (17922)
Matthijs Baart (799584)
Jeroen Huizingh (840122)
Jeroen Tolboom (606434)
Liesbeth Dekking (235102)
Jaap Goudsmit (17932)
Eirikur Saeland (799586)
Katarina Radošević (113341)

January 2016

Mice (n = 8-10/group) were immunized once with TVV+MM or PBS as negative control 4 weeks before c...

Survival curves of BALB/c mice inoculated with high viral titer.

Nan Huang (464390)
Navrozedeep Singh (464391)
Kyoungjin Yoon (464392)
Christina M. Loiacono (464393)
Marian L. Kohut (464394)
Diane F. Birt (464395)

September 2013

Kaplan-Meier survival curves of mice that received H. perforatum extract or 5% etha...

Influenza virus-primed mice maintain a Th1 profile following subsequent intranasal vaccination.

Asher Maroof (54053)
Yvonne M. Yorgensen (513817)
Yufeng Li (259327)
Jay T. Evans (513818)

January 2014

Control mice or mice primed with a non-lethal dose of Philippines/2/82/X-79, were subsequently va...

Protection of mice from lethal influenza virus challenge.

Maria del P. Martin (364367)
Shaguna Seth (364368)
Dimitrios G. Koutsonanos (314163)
Joshy Jacob (75952)
Richard W. Compans (111751)
Ioanna Skountzou (314165)

February 2013

Survival rates of immunized mice were monitored for 10 days after i.n. infection with mouse adapt...

Therapeutic efficacy of mAb 4E6 and 1H10 in a mouse model of H5N1 virus A/Vietnam/1194/04 infection.

Weixu Meng (338306)
Weiqi Pan (338308)
Anna J. X. Zhang (360354)
Zhengfeng Li (422880)
Guowei Wei (338305)
Liqiang Feng (422881)
Zhenyuan Dong (422882)
Chufang Li (422883)
Xiangjing Hu (422884)
Caijun Sun (422885)
Qinfang Luo (422886)
Kwok-Yung Yuen (2377228)
Nanshan Zhong (46591)
Ling Chen (25698)

June 2013

(A) The Kaplan-Meier survival curve. BALB/c mice (n=7 per group in two separate experiments) were...

Challenge of huN1-Immunized Mice with Influenza Viruses Possessing Homologous or Heterologous NA Genes

Matthew R Sandbulte (68599)
Gretchen S Jimenez (68600)
Adrianus C. M Boon (68601)
Larry R Smith (68602)
John J Treanor (68603)
Richard J Webby (36305)

February 2013

Mice immunized twice with huN1 DNA or saline alone (control) were inoculated intranasally with PR...

Immune protection of mice from lethal H5N1 (A and C) and H1N1 viral challenge (B and D).

Zenglin Pei (756363)
Xiaohong Jiang (29949)
Zhu Yang (756364)
Xiaoguang Ren (756365)
Hao Gong (127294)
Michael Reeves (756366)
Jingxue Sheng (756367)
Yu Wang (12152)
Zishu Pan (123907)
Fenyong Liu (13705)
Jianguo Wu (30201)
Sangwei Lu (205371)

June 2015

Groups of mice (n = 5) were intragastrically immunized three times at day 0, 14, and 28 with PBS ...

Protection of mice from lethal H7N7 influenza virus challenge.

Subaschandrabose Rajesh kumar (5663635)
Mookkan Prabakaran (266864)
Kattur Venkatachalam Ashok raj (5663638)
Fang He (43884)
Jimmy Kwang (61087)

June 2015

Mice (n = 10/groups) were immunized subcutaneously on day 0 and 28. All groups were challenged in...

An Ifitm locus deletion renders mice more susceptible to influenza.

Charles C. Bailey (137309)
I-Chueh Huang (137311)
Christina Kam (137314)
Michael Farzan (137316)

September 2012

IfitmDel knockout mice challenged intranasally with either 1000 or 500 PFU of influenza A/...

Protection against a highly pathogenic avian influenza virus H5N1 infection.

Qiang Zou (172269)
Yanxin Hu (172273)
Jia Xue (133314)
Xiaoxu Fan (172276)
Yi Jin (38575)
Xianghua Shi (172279)
Di Meng (172282)
Xianzheng Wang (172286)
Congcong Feng (172289)
Xiaoping Xie (172293)
Yizhi Zhang (172297)
Youmin Kang (172302)
Xiaoxuan Liang (172307)
Bing Wu (172312)
Ming Wang (172316)
Bin Wang (30851)

April 2012

Mice were challenged one month after vaccination (0.5 µg PZQ/0.1 µg antigen). (A) Viral loads in ...

Csf2−/− mice succumb to influenza virus infection despite intact antiviral T and B cell responses.

Christoph Schneider (413360)
Samuel P. Nobs (546911)
Alex K. Heer (546912)
Michael Kurrer (224262)
Glynis Klinke (546913)
Nico van Rooijen (4110211)
Johannes Vogel (515351)
Manfred Kopf (224264)

April 2014

(A–I) Indicated groups of mice were infected i.t. with PR8 influenza virus (50 pfu unless otherwi...

Survival of Mice Immunized with a Single Dose of H5N1 ca Vaccine Candidates Following Lethal Challenge with H5N1 1997 wt or H5N1 2004 wt Viruses

Amorsolo L Suguitan Jr. (274800)
Josephine McAuliffe (65599)
Kimberly L Mills (65600)
Hong Jin (65601)
Greg Duke (65602)
Bin Lu (65603)
Catherine J Luke (65604)
Brian Murphy (65605)
David E Swayne (65606)
George Kemble (65607)
Kanta Subbarao (65608)

February 2013

Groups of eight mice that received a single dose of 106 TCID50 of the H5N1 ...

Results following an H5N1 challenge of immunized mice.

Dominick J. Laddy (49838)
Jian Yan (49839)
Michele Kutzler (49840)
Darwyn Kobasa (18296)
Gary P. Kobinger (49841)
Amir S. Khan (49842)
Jack Greenhouse (49843)
Niranjan Y. Sardesai (49844)
Ruxandra Draghia-Akli (49845)
David B. Weiner (49846)

February 2013

Mice were challenged with 100LD50 of an H5N1 virus (A/Hanoi/05/2005). (a) Kaplan-Meier...

Serum from humans immunized with seasonal influenza vaccine protects mice against vaccine homologous H1 and heterosubtypic H5 influenza challenge.

Ramon Roozendaal (606433)
Jeroen Tolboom (606434)
Anna Roos (113323)
Sarra Riahi (606435)
Jessica Theeuwsen (606436)
Miriam V. Bujny (469450)
Vincent Klaren (495728)
Hans J. W. M. Korse (495730)
Liesbeth Dekking (235102)
Arijan Grootenhuis (606437)
Gerrit Jan Weverling (113348)
Wouter Koudstaal (367348)
Jaap Goudsmit (17932)
Katarina Radošević (113341)

July 2014

Kaplan-Meier survival curves (left), mean bodyweight change (middle) and median clinical score (r...

Dose-dependent protection against disease symptoms and death in H7N9-challenged DBA/2J mice immunized with whole-virus H7N9 vaccine.

Walter Wodal (362628)
Michael G. Schwendinger (486392)
Helga Savidis-Dacho (346034)
Brian A. Crowe (344547)
Christine Hohenadl (696217)
Richard Fritz (64050)
Peter Brühl (366856)
Daniel Portsmouth (346035)
Anita Karner-Pichl (696218)
Dalida Balta (696219)
Leopold Grillberger (366851)
Otfried Kistner (132940)
P. Noel Barrett (344551)
M. Keith Howard (346032)

February 2015

(A) Kaplan-Meier survival curves, (B) Severity and duration of disease symptoms</p

CD4+ and CD8+ T cells both contribute to H5N1 protection.

Freek Cox (17922)
Matthijs Baart (799584)
Jeroen Huizingh (840122)
Jeroen Tolboom (606434)
Liesbeth Dekking (235102)
Jaap Goudsmit (17932)
Eirikur Saeland (799586)
Katarina Radošević (113341)

January 2016

Mice (n = 8-10/group) were immunized once with TVV+MM or PBS as negative control 4 weeks before c...

Survival curves of BALB/c mice inoculated with high viral titer.

Nan Huang (464390)
Navrozedeep Singh (464391)
Kyoungjin Yoon (464392)
Christina M. Loiacono (464393)
Marian L. Kohut (464394)
Diane F. Birt (464395)

September 2013

Kaplan-Meier survival curves of mice that received H. perforatum extract or 5% etha...

Influenza virus-primed mice maintain a Th1 profile following subsequent intranasal vaccination.

Asher Maroof (54053)
Yvonne M. Yorgensen (513817)
Yufeng Li (259327)
Jay T. Evans (513818)

January 2014

Control mice or mice primed with a non-lethal dose of Philippines/2/82/X-79, were subsequently va...

Protection of mice from lethal influenza virus challenge.

Maria del P. Martin (364367)
Shaguna Seth (364368)
Dimitrios G. Koutsonanos (314163)
Joshy Jacob (75952)
Richard W. Compans (111751)
Ioanna Skountzou (314165)

February 2013

Survival rates of immunized mice were monitored for 10 days after i.n. infection with mouse adapt...

Therapeutic efficacy of mAb 4E6 and 1H10 in a mouse model of H5N1 virus A/Vietnam/1194/04 infection.

Weixu Meng (338306)
Weiqi Pan (338308)
Anna J. X. Zhang (360354)
Zhengfeng Li (422880)
Guowei Wei (338305)
Liqiang Feng (422881)
Zhenyuan Dong (422882)
Chufang Li (422883)
Xiangjing Hu (422884)
Caijun Sun (422885)
Qinfang Luo (422886)
Kwok-Yung Yuen (2377228)
Nanshan Zhong (46591)
Ling Chen (25698)

June 2013

(A) The Kaplan-Meier survival curve. BALB/c mice (n=7 per group in two separate experiments) were...

Challenge of huN1-Immunized Mice with Influenza Viruses Possessing Homologous or Heterologous NA Genes

Matthew R Sandbulte (68599)
Gretchen S Jimenez (68600)
Adrianus C. M Boon (68601)
Larry R Smith (68602)
John J Treanor (68603)
Richard J Webby (36305)

February 2013

Mice immunized twice with huN1 DNA or saline alone (control) were inoculated intranasally with PR...

Immune protection of mice from lethal H5N1 (A and C) and H1N1 viral challenge (B and D).

Zenglin Pei (756363)
Xiaohong Jiang (29949)
Zhu Yang (756364)
Xiaoguang Ren (756365)
Hao Gong (127294)
Michael Reeves (756366)
Jingxue Sheng (756367)
Yu Wang (12152)
Zishu Pan (123907)
Fenyong Liu (13705)
Jianguo Wu (30201)
Sangwei Lu (205371)

June 2015

Groups of mice (n = 5) were intragastrically immunized three times at day 0, 14, and 28 with PBS ...

Protection of mice from lethal H7N7 influenza virus challenge.

Subaschandrabose Rajesh kumar (5663635)
Mookkan Prabakaran (266864)
Kattur Venkatachalam Ashok raj (5663638)
Fang He (43884)
Jimmy Kwang (61087)

June 2015

Mice (n = 10/groups) were immunized subcutaneously on day 0 and 28. All groups were challenged in...

An Ifitm locus deletion renders mice more susceptible to influenza.

Charles C. Bailey (137309)
I-Chueh Huang (137311)
Christina Kam (137314)
Michael Farzan (137316)

September 2012

IfitmDel knockout mice challenged intranasally with either 1000 or 500 PFU of influenza A/...

Protection against a highly pathogenic avian influenza virus H5N1 infection.

Qiang Zou (172269)
Yanxin Hu (172273)
Jia Xue (133314)
Xiaoxu Fan (172276)
Yi Jin (38575)
Xianghua Shi (172279)
Di Meng (172282)
Xianzheng Wang (172286)
Congcong Feng (172289)
Xiaoping Xie (172293)
Yizhi Zhang (172297)
Youmin Kang (172302)
Xiaoxuan Liang (172307)
Bing Wu (172312)
Ming Wang (172316)
Bin Wang (30851)

April 2012

Mice were challenged one month after vaccination (0.5 µg PZQ/0.1 µg antigen). (A) Viral loads in ...

Csf2−/− mice succumb to influenza virus infection despite intact antiviral T and B cell responses.

Christoph Schneider (413360)
Samuel P. Nobs (546911)
Alex K. Heer (546912)
Michael Kurrer (224262)
Glynis Klinke (546913)
Nico van Rooijen (4110211)
Johannes Vogel (515351)
Manfred Kopf (224264)

April 2014

(A–I) Indicated groups of mice were infected i.t. with PR8 influenza virus (50 pfu unless otherwi...

Survival of Mice Immunized with a Single Dose of H5N1 ca Vaccine Candidates Following Lethal Challenge with H5N1 1997 wt or H5N1 2004 wt Viruses

Amorsolo L Suguitan Jr. (274800)
Josephine McAuliffe (65599)
Kimberly L Mills (65600)
Hong Jin (65601)
Greg Duke (65602)
Bin Lu (65603)
Catherine J Luke (65604)
Brian Murphy (65605)
David E Swayne (65606)
George Kemble (65607)
Kanta Subbarao (65608)

February 2013

Groups of eight mice that received a single dose of 106 TCID50 of the H5N1 ...

Kaplan-Meier survival curve in mice challenged with (a) H1N1 influenza (A/PR/8/34) and (b) H5N1 influenza (A/Vietnam/1203/04).

Abstract

Extracted data

Kaplan-Meier survival curve in mice challenged with (a) H1N1 influenza (A/PR/8/34) and (b) H5N1 influenza (A/Vietnam/1203/04).

Abstract

Extracted data

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