<p>The HSC response of TET-GFP mice + dox (middle panels) and H2B-GFP mice lacking the tetracycline-regulated tTA (bottom panels) are identical. Note in particular the level of GFP expression at day 13 in all three genotypes (far right column), the proportion of GFP<sup>+</sup> HSCs actually increased in TET-GFP mice +dox and H2B-GFP from day 6 to day 13.</p
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
<p>Flow cytometry profiles are as described in <a href="http://www.plosone.org/article/info:doi/10.1...
<p>Relative numbers of long-term and short-term (LT-HSC, ST-HSC) hematopoietic stem cells (<b>A.</b>...
<p>The HSCs of H2B-GFP mice show strong expression of GFP even in the absence of the tTA.</p
<p>Flow cytometry profiles of GFP expression in hematopoietic stem and progenitor cells isolated fro...
The study of adult stem cells relies on the ability to isolate them using complex combinations of ma...
<p>(A–D) Gating scheme used to identify mouse hematopoietic stem cells which were defined as side po...
The study of adult stem cells relies on the ability to isolate them using complex combinations of ma...
<p>A. Thymic sections prepared at the initiation of Dox feeding and from 2-6 weeks after the start o...
Data is shown as the mean fold change +/- SEM in the percentage of (A) HSC, (B) CMP and (C) CLP in 5...
<p>Proportion of GFP<sup>+</sup> cells in whole bone marrow and hematopoietic stem cell population f...
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
In studying hematopoietic stem cell (HSC) function in vivo, we discovered that HSCs from CXB-12/HiaJ...
We have previously demonstrated that young adult DBA/2 (DBA) mice have more stem cells than C57BL/6 ...
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
<p>Flow cytometry profiles are as described in <a href="http://www.plosone.org/article/info:doi/10.1...
<p>Relative numbers of long-term and short-term (LT-HSC, ST-HSC) hematopoietic stem cells (<b>A.</b>...
<p>The HSCs of H2B-GFP mice show strong expression of GFP even in the absence of the tTA.</p
<p>Flow cytometry profiles of GFP expression in hematopoietic stem and progenitor cells isolated fro...
The study of adult stem cells relies on the ability to isolate them using complex combinations of ma...
<p>(A–D) Gating scheme used to identify mouse hematopoietic stem cells which were defined as side po...
The study of adult stem cells relies on the ability to isolate them using complex combinations of ma...
<p>A. Thymic sections prepared at the initiation of Dox feeding and from 2-6 weeks after the start o...
Data is shown as the mean fold change +/- SEM in the percentage of (A) HSC, (B) CMP and (C) CLP in 5...
<p>Proportion of GFP<sup>+</sup> cells in whole bone marrow and hematopoietic stem cell population f...
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
In studying hematopoietic stem cell (HSC) function in vivo, we discovered that HSCs from CXB-12/HiaJ...
We have previously demonstrated that young adult DBA/2 (DBA) mice have more stem cells than C57BL/6 ...
The tetracycline (tet)-regulated expression system allows for the inducible overexpression of protei...
<p>Flow cytometry profiles are as described in <a href="http://www.plosone.org/article/info:doi/10.1...
<p>Relative numbers of long-term and short-term (LT-HSC, ST-HSC) hematopoietic stem cells (<b>A.</b>...