This figure illustrates the utilization of <i>iTools</i> for search, comparison and integration of bioinformatics tools.

<p>In this example, we demonstrate the use of the Basic Local Alignment Search Tool (BLAST) for comparing gene and protein sequences against other nucleic sequences available in various public databases. The <i>top row</i> shows <i>iTools</i> traversal and search (keyword = blast) using the hyperbolic graphical interface, and tools comparison and investigation of interoperability using the tabular resource view panel. The <i>bottom row</i> shows the design of a simple BLAST analysis workflow using one specific graphical workflow environment (LONI Pipeline). This BLAST analysis protocol depicts the NCBI DB formatting, index generation and filtering using <i>miBLAST</i>, sequence alignment and result textual visualization.