Sn expression on CD14⁺ monocytes from HIV seropositive individuals.

<p>(A) Representative frequency histograms of relative Sn expression on CD14⁺ monocytes isolated from subjects with high viral load (HVL, 214,000 RNA copies/ml, thick black line), low viral load (LVL, 6,350 RNA copies/ml, thin black line) and a seronegative control (dotted line). The isotype-matched control mAb is shown in the shaded profile. (B) Correlation analysis of Sn expression and viral load. Sn expression on CD14⁺ monocytes from HIV seropositive subjects (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001967#pone-0001967-t001" target="_blank">Table 1</a>, n = 24) was determined by flow cytometry and quantified as a geometric mean for each subject. Pearson's correlation analysis showed statistical significance between Sn expression and the log of the subject's viral load (p<0.0017). (C) Correlation analysis of Sn expression and CD4 (counts/ml) revealed no significant relationship (p<0.08).