Activation in frontal and temporal regions during the different ToM conditions.

<p>The graph shows the mean signal intensity (+/− s.e.m.) (in arbitrary units) in these regions in the conditions DEC (black), COOP (white) and COOPDEC (grey), respectively. The ANOVA with the factors condition and region showed main effects of condition (F(2) = 7.917 p<0.001, region (F(2) = 4.830 p<0.01 and a significant condition*region interaction (F(4) = 9.910 p<0.001 with significantly higher activation in medial prefrontal cortex during DEC compared to COOP and COOPDEC (t(12) = 2.537 p<0.01 and t(12) = 2.290 p<0.01, respectively); in inferior frontal cortex during DEC and COOPDEC compared to COOP (t(12) = 3.041 p<0.01 and t(12) = 4.005 p<0.001), and in temporoparietal junction in COOPDEC compared to DEC (t(12) = 2.079 p<0.01) and COOP (t(12) = 4.173 p<0.001). Activation during DEC was significantly higher in medial PFC than in TPJ (t(12) = 3.179 p<0.01), and during COOP and COOPDEC significantly higher in TPJ than in inferior frontal gyrus (t(12) = 3.726 p<0.01 and t(12) = 2.757 p<0.01).