<p>Representative current traces of mutant R237W expressed without (A) or with KCNE1 (B). Conductance-voltage relations (C) and current-voltage relations (D) of WT Kv7.1 and mutant R237W co-expressed with KCNE1. Representative current traces of mutant R243W expressed without (E) or with KCNE1 (F). Conductance-voltage relations (G) and current-voltage relations (H) of WT Kv7.1 and mutant R243W co-expressed with KCNE1.</p
<p>Changes in parameters of steady-state variables and maximum conductance of <i>I</i><sub>Kur</sub>...
<p>(A) and (B) Representative current traces of WT and L233W and Q244W, respectively, recorded as in...
<p>(A) Current/voltage relation of unitary channel currents generated by wt-PLN (full squares), K27A...
<p>Representative current traces of mutant R231W expressed without (A) or with KCNE1 (B). Conductanc...
<p>(A) Representative trace of WT Kv7.1 coexpressed with WT KCNE1. (B) Effects of external Cu-Phen o...
<p>A) voltage-dependent activation curves, and B) normalized activation curves. Curves were fitted u...
<p>N = 6.</p><p>Abbreviations: V<sub>h</sub> voltage at which half the channels are activated; ΔG(C→...
<p>A) rates of activation, and B) current density from CHO cells transiently expressing Myc-tagged K...
SummaryThe voltage-gated potassium channel Kv7.1 and its auxiliary subunit KCNE1 are expressed in th...
<p>A) Current traces, with deactivation protocol in inset, and B) rates of deactivation plotted agai...
<p>A) Co-immunoprecipitation of wild-type and mutant KCNE1 with KCNQ1. KCNQ1 (Q1) was expressed with...
<p>A series of 100 pulses mimicked action potential trains at three rates: 60, 120, or 150 per minut...
Kv7 potassium channels whose mutations cause cardiovascular and neurological disorders are members o...
AbstractThe KCNE1 auxiliary subunit coassembles with the Kv7.1 channel and modulates its properties ...
<p>(A–E) Current traces recorded from oocytes injected with (A) Kv12.2 cRNA only, or co-injected (B)...
<p>Changes in parameters of steady-state variables and maximum conductance of <i>I</i><sub>Kur</sub>...
<p>(A) and (B) Representative current traces of WT and L233W and Q244W, respectively, recorded as in...
<p>(A) Current/voltage relation of unitary channel currents generated by wt-PLN (full squares), K27A...
<p>Representative current traces of mutant R231W expressed without (A) or with KCNE1 (B). Conductanc...
<p>(A) Representative trace of WT Kv7.1 coexpressed with WT KCNE1. (B) Effects of external Cu-Phen o...
<p>A) voltage-dependent activation curves, and B) normalized activation curves. Curves were fitted u...
<p>N = 6.</p><p>Abbreviations: V<sub>h</sub> voltage at which half the channels are activated; ΔG(C→...
<p>A) rates of activation, and B) current density from CHO cells transiently expressing Myc-tagged K...
SummaryThe voltage-gated potassium channel Kv7.1 and its auxiliary subunit KCNE1 are expressed in th...
<p>A) Current traces, with deactivation protocol in inset, and B) rates of deactivation plotted agai...
<p>A) Co-immunoprecipitation of wild-type and mutant KCNE1 with KCNQ1. KCNQ1 (Q1) was expressed with...
<p>A series of 100 pulses mimicked action potential trains at three rates: 60, 120, or 150 per minut...
Kv7 potassium channels whose mutations cause cardiovascular and neurological disorders are members o...
AbstractThe KCNE1 auxiliary subunit coassembles with the Kv7.1 channel and modulates its properties ...
<p>(A–E) Current traces recorded from oocytes injected with (A) Kv12.2 cRNA only, or co-injected (B)...
<p>Changes in parameters of steady-state variables and maximum conductance of <i>I</i><sub>Kur</sub>...
<p>(A) and (B) Representative current traces of WT and L233W and Q244W, respectively, recorded as in...
<p>(A) Current/voltage relation of unitary channel currents generated by wt-PLN (full squares), K27A...