Test-retest concordance of two QFT tests performed on the same set of specimens (N = 56 paired specimens from 14 subjects)

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

Publication date

February 2013

DOI

10.1371/journal.pone.0001850.t003

Abstract

Concordance = 96.4%; κ = 0.94*The cut-off value for a positive QFT test was IFN-γ≥0.35 IU/mLQFT: QuantiFERON-TB Gold In Tube®; IFN-γ: interferon-gamma.</p

Extracted data

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Data Protection

Test-retest concordance of two QFT tests performed on the same set of specimens (N = 56 paired specimens from 14 subjects)

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

Open link

Publication date

February 2013

DOI

10.1371/journal.pone.0001850.t003

Abstract

Concordance = 96.4%; κ = 0.94*The cut-off value for a positive QFT test was IFN-γ≥0.35 IU/mLQFT: QuantiFERON-TB Gold In Tube®; IFN-γ: interferon-gamma.</p

Extracted data

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

Within-person variability in initial QFT results (14 individuals tested 4 times on day 0, 3, 9 and 12)

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

QFT: QuantiFERON-TB Gold In Tube®; IFN-γ: interferon-gamma*The cut-off value for a positiv...

Test versus re-test QFT results expressed as IFN-γ (IU/mL).

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

Data for each individual is plotted with different symbols, and the line of equality is shown as ...

Raw data for the two individuals with discordant QFT results; both individuals had discordant between-test results and discordant within-person results*

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

*Complete QFT results for both individuals are shown in <a href="http://www.plosone.org/article/i...

Median and mean IFN-γ measurements for QuantiFERON-TB Gold In-Tube tests performed on the same subjects in three labs.

William C. Whitworth (137545)
Lanette R. Hamilton (137549)
Donald J. Goodwin (137553)
Carlos Barrera (137557)
Kevin B. West (137561)
Laura Racster (137564)
Laura J. Daniels (137567)
Stella O. Chuke (137569)
Brandon H. Campbell (137572)
Jamaria Bohanon (137575)
Atheer T. Jaffar (137577)
Wanzer Drane (137580)
David Maserang (137584)
Gerald H. Mazurek (137587)

September 2012

Nil = IFN-γ concentrations (IU/mL) in plasma from the Nil tube of the QuantiFERON-TB Gold In-Tube...

Difference in QFT results (test–re-test) versus the average of QFT test and re-test results (all on the log scale).

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

Separate plotting characters are used for each individual and the mean log-difference is shown as...

Within person variability of log IFN-γ responses over 4 time points (day 0, 3, 9 and 12).

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

Separate plotting characters are used for each individual (N = 14) who underwent 4 QFT assays on ...

Variability in Quantiferon-TB Gold in-Tube test measurements performed on the same subjects in three labs excluding those with extremely high TB Response.

William C. Whitworth (137545)
Lanette R. Hamilton (137549)
Donald J. Goodwin (137553)
Carlos Barrera (137557)
Kevin B. West (137561)
Laura Racster (137564)
Laura J. Daniels (137567)
Stella O. Chuke (137569)
Brandon H. Campbell (137572)
Jamaria Bohanon (137575)
Atheer T. Jaffar (137577)
Wanzer Drane (137580)
David Maserang (137584)
Gerald H. Mazurek (137587)

September 2012

*LOA, bias, SDD, and W-S SD are in IU/mL of IFN-γ.†Directionality for bias and LOA compari...

The response of QuantiFERON-TB Gold In-tube (QFT-GIT), calculated by the interferon-γ level in TB-antigen tube minus that in the negative control, are shown in all and those with positive QFT-GIT according to the different groups.

Chin-Chung Shu (162563)
Chia-Lin Hsu (58761)
Chih-Yuan Lee (731291)
Jann-Yuan Wang (162575)
Vin-Cent Wu (111853)
Feng-Jung Yang (310746)
Jann-Tay Wang (195783)
Chong-Jen Yu (58765)
Li-Na Lee (162583)

April 2015

The response of QuantiFERON-TB Gold In-tube (QFT-GIT), calculated by the interferon-γ level in TB...

A multicentre verification study of the QuantiFERON®-TB Gold Plus assay

Pieterman, E. D.
Liqui Lung, F. G.
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives The aim of this verification study was to compare the QuantiFERON®-TB Gold Plus (QFT-Plus...

A multicentre verification study of the QuantiFERON®-TB Gold Plus assay

Pieterman, E. D.
Liqui Lung, F. G.
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives The aim of this verification study was to compare the QuantiFERON®-TB Gold Plus (QFT-Plus...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

Within-person variability in initial QFT results (14 individuals tested 4 times on day 0, 3, 9 and 12)

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

QFT: QuantiFERON-TB Gold In Tube®; IFN-γ: interferon-gamma*The cut-off value for a positiv...

Test versus re-test QFT results expressed as IFN-γ (IU/mL).

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

Data for each individual is plotted with different symbols, and the line of equality is shown as ...

Raw data for the two individuals with discordant QFT results; both individuals had discordant between-test results and discordant within-person results*

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

*Complete QFT results for both individuals are shown in <a href="http://www.plosone.org/article/i...

Median and mean IFN-γ measurements for QuantiFERON-TB Gold In-Tube tests performed on the same subjects in three labs.

William C. Whitworth (137545)
Lanette R. Hamilton (137549)
Donald J. Goodwin (137553)
Carlos Barrera (137557)
Kevin B. West (137561)
Laura Racster (137564)
Laura J. Daniels (137567)
Stella O. Chuke (137569)
Brandon H. Campbell (137572)
Jamaria Bohanon (137575)
Atheer T. Jaffar (137577)
Wanzer Drane (137580)
David Maserang (137584)
Gerald H. Mazurek (137587)

September 2012

Nil = IFN-γ concentrations (IU/mL) in plasma from the Nil tube of the QuantiFERON-TB Gold In-Tube...

Difference in QFT results (test–re-test) versus the average of QFT test and re-test results (all on the log scale).

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

Separate plotting characters are used for each individual and the mean log-difference is shown as...

Within person variability of log IFN-γ responses over 4 time points (day 0, 3, 9 and 12).

Anandharaman Veerapathran (88755)
Rajnish Joshi (88756)
Kalyan Goswami (88757)
Sandeep Dogra (88758)
Erica E. M. Moodie (88759)
M. V. R. Reddy (88760)
Shriprakash Kalantri (88761)
Kevin Schwartzman (66114)
Marcel A. Behr (88762)
Dick Menzies (66118)
Madhukar Pai (55924)

February 2013

Separate plotting characters are used for each individual (N = 14) who underwent 4 QFT assays on ...

Variability in Quantiferon-TB Gold in-Tube test measurements performed on the same subjects in three labs excluding those with extremely high TB Response.

William C. Whitworth (137545)
Lanette R. Hamilton (137549)
Donald J. Goodwin (137553)
Carlos Barrera (137557)
Kevin B. West (137561)
Laura Racster (137564)
Laura J. Daniels (137567)
Stella O. Chuke (137569)
Brandon H. Campbell (137572)
Jamaria Bohanon (137575)
Atheer T. Jaffar (137577)
Wanzer Drane (137580)
David Maserang (137584)
Gerald H. Mazurek (137587)

September 2012

*LOA, bias, SDD, and W-S SD are in IU/mL of IFN-γ.†Directionality for bias and LOA compari...

Chin-Chung Shu (162563)
Chia-Lin Hsu (58761)
Chih-Yuan Lee (731291)
Jann-Yuan Wang (162575)
Vin-Cent Wu (111853)
Feng-Jung Yang (310746)
Jann-Tay Wang (195783)
Chong-Jen Yu (58765)
Li-Na Lee (162583)

April 2015

The response of QuantiFERON-TB Gold In-tube (QFT-GIT), calculated by the interferon-γ level in TB...

A multicentre verification study of the QuantiFERON®-TB Gold Plus assay

Pieterman, E. D.
Liqui Lung, F. G.
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives The aim of this verification study was to compare the QuantiFERON®-TB Gold Plus (QFT-Plus...

A multicentre verification study of the QuantiFERON®-TB Gold Plus assay

Pieterman, E. D.
Liqui Lung, F. G.
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives The aim of this verification study was to compare the QuantiFERON®-TB Gold Plus (QFT-Plus...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

A multicentre verification study of the QuantiFERON (R)-TB Gold Plus assay

Pieterman, E. D.
Lung, F. G. Liqui
Verbon, A.
Bax, H. I.
Ang, C. W.
Berkhout, J.
Blaauw, G.
Brandenburg, A.
van Burgel, N. D.
Claessen, A.
van Dijk, K.
Heron, M.
Hooghiemstra, M.
Leussenkamp-Hummelink, R.
van Lochem, E.
van Loo, I. H. M.
Mulder, B.
Ott, A.
Pontesilli, O.
Reuwer, A.
Rombouts, P.
Saegeman, V.
Scholing, M.
Vainio, S.
de Steenwinkel, J. E. M.

January 2018

Objectives: The aim of this verification study was to compare the QuantiFERON (R)-TB Gold Plus (QFT-...

Test-retest concordance of two QFT tests performed on the same set of specimens (N = 56 paired specimens from 14 subjects)

Abstract

Extracted data

Test-retest concordance of two QFT tests performed on the same set of specimens (N = 56 paired specimens from 14 subjects)

Abstract

Extracted data

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