<p>Data are means of log<sub>10</sub> of cfu numbers recovered from 77 mice infected over six independent experiments. Bars = Standard Errors. Stars indicate that the data are significantly different between the two <i>Yersinia</i> species (p≤0.0001). The dashed line shows the detection limit (10 cfu). The cross symbol indicates that most <i>Y. pestis</i>-infected mice died between days 2 and 3.</p
<p>(A) Total cell numbers of innate immune cell populations in the lungs of mice inoculated with 10<...
<p>(A) Bacterial burden in LN (circles) and ears (triangles) harvested at 24 hpi from mice inoculate...
(A-B) Groups of 5–9 C57Bl/6J mice were challenged by intranasal instillation with 2,000 (circles) or...
<p>(A and B) Southern dot blot analysis of DNA from bacteria from (A) LNs harvested at 12 hpi and (B...
<p>A group of 5 mice each were infected intravenously with 10<sup>5</sup> CFU of TIGR4 or Δ<i>idtr</...
<p>(A) CFUs of the Δ<i>frvA</i> and Δ<i>frvA</i> complemented strain enumerated from livers and sple...
<p>(A) Blood was taken from the tail vein of young, middle-aged, and aged mice 12, 24, or 48 h after...
<p>Mice were challenged with CO92 (113,000 CFU) or Δ<i>tatA</i> mutant (76,000 CFU). At set time poi...
<p>(A–B) Wild type female C57BL/6 mice were challenged by intranasal infection with <i>Y. pestis</i>...
<p>Strains are ordered by increasing mean survival time post-infection. A) Bacterial count in blood ...
Groups of 5–6 C57Bl/6J mice were challenged by intranasal infection with 10μL containing 2,000 CFU w...
<p>(<i>A</i>) Survival time of mice after infection with approximately 1 X 10<sup>6</sup> CFU pneumo...
<p>Mice were infected with a 1:1:1 mixture of 3 resistance marker tagged NewHG variants and 5 mice s...
<p>Groups of three mice were infected with nonlethal <i>P. yoelii 17XNL</i> or lethal P <i>yoelii YM...
<p>Mice were killed at week 21 (A) and week 43 (B) after infection. Asterisks show strains that exhi...
<p>(A) Total cell numbers of innate immune cell populations in the lungs of mice inoculated with 10<...
<p>(A) Bacterial burden in LN (circles) and ears (triangles) harvested at 24 hpi from mice inoculate...
(A-B) Groups of 5–9 C57Bl/6J mice were challenged by intranasal instillation with 2,000 (circles) or...
<p>(A and B) Southern dot blot analysis of DNA from bacteria from (A) LNs harvested at 12 hpi and (B...
<p>A group of 5 mice each were infected intravenously with 10<sup>5</sup> CFU of TIGR4 or Δ<i>idtr</...
<p>(A) CFUs of the Δ<i>frvA</i> and Δ<i>frvA</i> complemented strain enumerated from livers and sple...
<p>(A) Blood was taken from the tail vein of young, middle-aged, and aged mice 12, 24, or 48 h after...
<p>Mice were challenged with CO92 (113,000 CFU) or Δ<i>tatA</i> mutant (76,000 CFU). At set time poi...
<p>(A–B) Wild type female C57BL/6 mice were challenged by intranasal infection with <i>Y. pestis</i>...
<p>Strains are ordered by increasing mean survival time post-infection. A) Bacterial count in blood ...
Groups of 5–6 C57Bl/6J mice were challenged by intranasal infection with 10μL containing 2,000 CFU w...
<p>(<i>A</i>) Survival time of mice after infection with approximately 1 X 10<sup>6</sup> CFU pneumo...
<p>Mice were infected with a 1:1:1 mixture of 3 resistance marker tagged NewHG variants and 5 mice s...
<p>Groups of three mice were infected with nonlethal <i>P. yoelii 17XNL</i> or lethal P <i>yoelii YM...
<p>Mice were killed at week 21 (A) and week 43 (B) after infection. Asterisks show strains that exhi...
<p>(A) Total cell numbers of innate immune cell populations in the lungs of mice inoculated with 10<...
<p>(A) Bacterial burden in LN (circles) and ears (triangles) harvested at 24 hpi from mice inoculate...
(A-B) Groups of 5–9 C57Bl/6J mice were challenged by intranasal instillation with 2,000 (circles) or...