Survival in the Nose of the Wild-Type Strain versus the Mutant Strain

<div><p>(A) Kaplan-Meier survival curve of the 8325–4 S. aureus (solid line) and its <i>ClfB⁻</i> mutant (DU5997) strain (dashed line) in human nose (last cultured strain in either nostril). All cells of the mutant strain were eliminated after a period of 14 d, which is significantly faster than the elimination rate for the 8325–4 S. aureus strain.</p> <p>(B) Kaplan-Meier survival curve of the 8325–4 S. aureus (WT) and <i>ClfB⁻</i> mutant (DU5997; dashed line) that were inoculated together as a mix in one nostril.</p> <p>(C) Number of cfu of 8325–4 and DU5997 in follow-up samples.</p>