<p>Data from Experiments #1, 2, and 3 are plotted. Data from Control animals are not included. Panel A shows PkCSP endpoint ELISA titers where there is no significant correlation. Panel B shows PkCSP interferon-γ ELIspot titers with a linear regression line included. There is a significant negative correlation (p = 0.04), animals with lower ELIspot responses having longer times to the appearance of first parasite in the blood.</p
<p>Correlation of Spearman between parasite load at popliteal lymph nodes with clinical score after ...
<p>(<b>A</b>) Mean and standard deviations log<sub>10</sub> values of parasitemia in mice immunized ...
<p><b>Panel A</b>: Parasitemia-free survival curves (Kaplan-Meier) for immunized volunteers and infe...
Animals in cohorts 1 and 2 were challenged with 100 PK Spz on day 273 after the first inoculation wi...
Each cohort was challenged with 100 Spz at day 0 and blood stage parasitemia was monitored daily by ...
<p>Animals were vaccinated with either <i>E. coli</i> or baculovirus expressed MSP1<sub>42</sub> in ...
<p>Vaccine and challenge groups, animal ID, ELISA endpoint titer against 3D7 or FVO AMA1 coated plat...
(A, B) Endpoint titers of IgG antibodies in serum collected from cohort 1 (RhCMV/PK4) or cohort 2 (Δ...
<p>After the third DNA vaccination, the PkCSP 5.0 mg group has the highest response but this is not ...
<p>The means of the percent infected erythrocytes (A) or PCV (B) for each group of animals are plott...
<p>‘Day 1<sup>st</sup> parasite’ is the day after sporozite challenge when a parasite was first seen...
Graphs show fold changes of mucosal IgG antibodies to each PCS peptide (1 through 12) between the ti...
Reactivity of canine sera assessed using EIE-LVC kit (A-B), analyzed with two cut-off values; rK39 (...
<p>Changes in cFABP, TnI, CK and CK-MB in control animals and the shock group at baseline and 1, 3 a...
<p>(A) IFN-γ responses in vaccinated and nonvaccinated animals following vaccination and after chall...
<p>Correlation of Spearman between parasite load at popliteal lymph nodes with clinical score after ...
<p>(<b>A</b>) Mean and standard deviations log<sub>10</sub> values of parasitemia in mice immunized ...
<p><b>Panel A</b>: Parasitemia-free survival curves (Kaplan-Meier) for immunized volunteers and infe...
Animals in cohorts 1 and 2 were challenged with 100 PK Spz on day 273 after the first inoculation wi...
Each cohort was challenged with 100 Spz at day 0 and blood stage parasitemia was monitored daily by ...
<p>Animals were vaccinated with either <i>E. coli</i> or baculovirus expressed MSP1<sub>42</sub> in ...
<p>Vaccine and challenge groups, animal ID, ELISA endpoint titer against 3D7 or FVO AMA1 coated plat...
(A, B) Endpoint titers of IgG antibodies in serum collected from cohort 1 (RhCMV/PK4) or cohort 2 (Δ...
<p>After the third DNA vaccination, the PkCSP 5.0 mg group has the highest response but this is not ...
<p>The means of the percent infected erythrocytes (A) or PCV (B) for each group of animals are plott...
<p>‘Day 1<sup>st</sup> parasite’ is the day after sporozite challenge when a parasite was first seen...
Graphs show fold changes of mucosal IgG antibodies to each PCS peptide (1 through 12) between the ti...
Reactivity of canine sera assessed using EIE-LVC kit (A-B), analyzed with two cut-off values; rK39 (...
<p>Changes in cFABP, TnI, CK and CK-MB in control animals and the shock group at baseline and 1, 3 a...
<p>(A) IFN-γ responses in vaccinated and nonvaccinated animals following vaccination and after chall...
<p>Correlation of Spearman between parasite load at popliteal lymph nodes with clinical score after ...
<p>(<b>A</b>) Mean and standard deviations log<sub>10</sub> values of parasitemia in mice immunized ...
<p><b>Panel A</b>: Parasitemia-free survival curves (Kaplan-Meier) for immunized volunteers and infe...