<p>Embryonic Day 9.5 and 10.5 mp66α −/− Embryos. Mutant embryos, significantly smaller, are shown in comparison with wild-type littermates. Abnormalities in mp66α null embryos around day 9.5 (A, B) include malformed and non-fused neural folds, failure of closure of anterior neuropore, missing or excessively large blood vessels in the yolk sac, Day 10.5 embryos (C,D) are disintegrating due to multiple defects.</p
<p>(A–F) Stage ∼13 embryos, ventral aspect. A and B are triple labelings of Deadpan (NB), Prospero (...
<p>Embryos were fixed after 15–20 hours AED and stained for microtubules (green) and DNA (red). (A) ...
<p>Lateral views of embryos at 24 hpf (A–C), 48hpf (D–F) or at 96 hpf (G–L). (A) Wild-type (WT) embr...
<p>(<b>A</b>) Wild-type embryo at E8.5. Mutant Ikbkap<sup>3loxP/3loxP</sup> (<b>B</b>) and Ikbkap<su...
<p>At 8.5 dpc mutant embryos are indistinguishable from their wild-type littermates. From 9.5 dpc on...
<p>(<b>A–F</b>) H&E-stained transverse sections through the head of E9.5 WT (<b>A</b> and <b>D</b>),...
Item does not contain fulltextNeural tube defects, mostly believed to result from closure defects of...
Background: Identifying genes that are essential for mouse embryonic development and survival throug...
<p>Wild-type E11.5 embryo (A–E) compared to a mutant littermate (F–J) that expresses the <i>Pax3:Fkh...
<p>A-L) Bright field images of WT (A–F) and cKO (G–L) embryos (EM) alone or embryos within their yol...
<p>(A), the wild type (+/+) and mutant (−/−) embryos at E10.5 were stained using PECAM-1. (B), HE st...
<p>Images of neuromuscular bouton profiles (A–H) and close-ups of their respective synapses (A′–H′) ...
<p>Total number of embryos recovered at each stage is indicated; number of dead embryos is included ...
<p>A: <i>ptp-3(mu245)</i> mutant animals can hatch as normal looking L1 larvae (arrow), but can also...
Analysis of the embryonic phenotype of Bent tail, a mouse model for X-linked neural tube defects.Fra...
<p>(A–F) Stage ∼13 embryos, ventral aspect. A and B are triple labelings of Deadpan (NB), Prospero (...
<p>Embryos were fixed after 15–20 hours AED and stained for microtubules (green) and DNA (red). (A) ...
<p>Lateral views of embryos at 24 hpf (A–C), 48hpf (D–F) or at 96 hpf (G–L). (A) Wild-type (WT) embr...
<p>(<b>A</b>) Wild-type embryo at E8.5. Mutant Ikbkap<sup>3loxP/3loxP</sup> (<b>B</b>) and Ikbkap<su...
<p>At 8.5 dpc mutant embryos are indistinguishable from their wild-type littermates. From 9.5 dpc on...
<p>(<b>A–F</b>) H&E-stained transverse sections through the head of E9.5 WT (<b>A</b> and <b>D</b>),...
Item does not contain fulltextNeural tube defects, mostly believed to result from closure defects of...
Background: Identifying genes that are essential for mouse embryonic development and survival throug...
<p>Wild-type E11.5 embryo (A–E) compared to a mutant littermate (F–J) that expresses the <i>Pax3:Fkh...
<p>A-L) Bright field images of WT (A–F) and cKO (G–L) embryos (EM) alone or embryos within their yol...
<p>(A), the wild type (+/+) and mutant (−/−) embryos at E10.5 were stained using PECAM-1. (B), HE st...
<p>Images of neuromuscular bouton profiles (A–H) and close-ups of their respective synapses (A′–H′) ...
<p>Total number of embryos recovered at each stage is indicated; number of dead embryos is included ...
<p>A: <i>ptp-3(mu245)</i> mutant animals can hatch as normal looking L1 larvae (arrow), but can also...
Analysis of the embryonic phenotype of Bent tail, a mouse model for X-linked neural tube defects.Fra...
<p>(A–F) Stage ∼13 embryos, ventral aspect. A and B are triple labelings of Deadpan (NB), Prospero (...
<p>Embryos were fixed after 15–20 hours AED and stained for microtubules (green) and DNA (red). (A) ...
<p>Lateral views of embryos at 24 hpf (A–C), 48hpf (D–F) or at 96 hpf (G–L). (A) Wild-type (WT) embr...
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