Efficiency Measures for Low-Cost Brain Functional Networks, with <i>K</i> ∼ 0.1, in All Participants

<div><p>(Top row) Within-subject effects of dopamine antagonism (sulpiride 400 mg) on global efficiency (left column), local efficiency (middle column), and maximum cost efficiency (right column): data on younger subjects are denoted by black lines and black triangles, data on older subjects by red lines and red triangles.</p><p>(Bottom row) Box-plots showing median, interquartile range, and range for global efficiency, local efficiency, and maximum-cost efficiency in each age group after each treatment. Each horizontal line and the associated number represent the <i>p</i>-value of a post-hoc <i>t</i>-test: there were consistent pairwise differences in global efficiency related to age (YP–OP and YS–OS), less consistent age-related differences in cost efficiency (YP–OP), and no significant post-hoc effects of age on local efficiency; however, there were consistent pairwise differences in local efficiency related to drug treatment (YP–YS and OP–OS), and a significant effect of drug on global efficiency in young people (YP–YS).</p>