Experimental Design for Assessing the Therapeutic Effect of the Cysteine Protease Inhibitor K11777 on Mice Infected with S. mansoni

<p>All mice were infected with 150 S. mansoni cercariae injected subcutaneously. K11777 was administered intraperitoneally in 100 μl of water at the dosages and timings indicated. Control mice received water alone. All mice were perfused at 49 days p.i., and worm and egg burdens and organ pathology were assessed.