The Nine Members of the Gastrula Defect Phenotypic Class

<p>Note that the blastopore in control embryos is closing normally, but is either absent or severely delayed in embryos in which the functions of the indicated genes are inhibited. All embryos shown are at gastrula stage 10.5 to 11.5. In this figure and in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0020193#pgen-0020193-g005" target="_blank">Figures 5</a>–<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0020193#pgen-0020193-g013" target="_blank">13</a>, the number in the top left hand side of each panel represents the synphenotype group to which the embryos belong, and the name of the gene in question is shown bottom left.