Interdigitated Intracortical Relays

<div><p>(A) Average synaptic input maps for positionally defined L2/3 pyramidal cells.</p> <p>(B) Regions of interest used for the analysis in (C–E).</p> <p>(C) The ratio of input from L5A/L4 as a function of the depth of the soma of barrel-related neurons. Dashed black line (top) indicates the pia.</p> <p>(D) The ratio of input from L2/3/L4.</p> <p>(E) Average synaptic input for projections defined by the presynaptic layer, postsynaptic layer, and postsynaptic column. For L3 neurons in septum and barrels, L4 input is significantly stronger than L5A input; for L2 neurons in barrels, L5A input is significantly stronger than L4 input (<i>p</i> < 0.005, Wilcoxon). Note that this pattern differs from that measured in the rat using essentially identical techniques (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0040382#pbio-0040382-g003" target="_blank">Figure 3</a>e in [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0040382#pbio-0040382-b013" target="_blank">13</a>]). L3 input is significantly stronger for L2/3^Septum cells than for L2/3^Barrel cells (<i>p</i> < 0.05, Wilcoxon).</p> <p>(F) Horizontal profiles of L4 input to L3 cells.</p> <p>(G) Horizontal profiles of L5A input to L2 cells.</p>