Cell-Based Delivery of VEGF to Muscle

<div><p>The total VEGF expression in each of the tissues (A–F) is the same; the arrangement delivery of VEGF from cells incorporated into each tissue is different. Stars mark the fiber(s) that overexpress VEGF. VEGF gradients and capillary activation graphs are as for <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020127#pcbi-0020127-g002" target="_blank">Figure 2</a>.</p><p>(A) 40-Fold overexpression of VEGF in one fiber.</p><p>(B) Uniform 1.33-fold overexpression of VEGF by all fibers.</p><p>(C,D) 20-Fold overexpression of VEGF in two fibers, close together (C) or distant (D).</p><p>(E,F) 13.3-Fold overexpression of VEGF in three fibers, close together (E) or distant (F).</p>