<p>(<b>A</b>) Frequency of HCV-tetramer<sup>+</sup> CD8<sup>+</sup> T cells after 10 days <i>in vitro</i> expansion for patients (n = 28) grouped above or below the median for sCD26. (<b>B</b>) Frequency of IFN-γ<sup>+</sup> CD8<sup>+</sup> T cells after 10 days <i>in vitro</i> expansion for patients (n = 28) grouped above or below the median for sCD26. Statistic using two-tailed Mann-Whitney U-test.</p
<p>(A) Pre- and on-treatment FACS density plots in response to a 5.5 hour incubation with 2 µgml<sup...
<p>Antiviral efficacy (white bars) and functional avidity (filled circles) of CTL lines, derived fro...
<p>Whole PBMC or PBMC depleted of either CD4<sup>+</sup> or CD8<sup>+</sup> T cells from 17 HCMV ser...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining of a CTL line expose...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining with CD8+ T cells fr...
<p>Proliferation of HIV- and HCV-specific CD4 and CD8 T cells in response to HIV P24 (A, B) and HCV ...
Results are presented per subjects with from top to bottom: (HCV RNA) Viremia status presented as vi...
<p>PBMCs from 7 chronically HCV monoinfected individuals and 10 HIV/HCV coinfected individuals were ...
<p>(A) CD4<sup>+</sup> (top panel) and CD8<sup>+</sup> (bottom panel) naïve T-cell counts were quant...
<p>(<b>A</b>) Increased frequency of Tregs in CI patients during late acute HCV. Regulatory T cells ...
a<p>log<sub>10</sub> IU/ml.</p>b<p>By trypan blue count; visits during and following treatment.</p>c...
<p>(A) Cytokine production and CD107a mobilization of CTL lines, derived from chronically HCV infect...
<p>Resting and activated CD8 T cells were defined as CD127<sup>+</sup>CD38<sup>neg</sup> and HLA-DR<...
<p>(<b>A,B</b>) A quantitative analysis of IFN-γ production was performed in HD (n = 35, Panel A) an...
<p>CD25-depleted PBMC from patients with acute HCV infection (SR or CI) were stained with CFSE and s...
<p>(A) Pre- and on-treatment FACS density plots in response to a 5.5 hour incubation with 2 µgml<sup...
<p>Antiviral efficacy (white bars) and functional avidity (filled circles) of CTL lines, derived fro...
<p>Whole PBMC or PBMC depleted of either CD4<sup>+</sup> or CD8<sup>+</sup> T cells from 17 HCMV ser...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining of a CTL line expose...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining with CD8+ T cells fr...
<p>Proliferation of HIV- and HCV-specific CD4 and CD8 T cells in response to HIV P24 (A, B) and HCV ...
Results are presented per subjects with from top to bottom: (HCV RNA) Viremia status presented as vi...
<p>PBMCs from 7 chronically HCV monoinfected individuals and 10 HIV/HCV coinfected individuals were ...
<p>(A) CD4<sup>+</sup> (top panel) and CD8<sup>+</sup> (bottom panel) naïve T-cell counts were quant...
<p>(<b>A</b>) Increased frequency of Tregs in CI patients during late acute HCV. Regulatory T cells ...
a<p>log<sub>10</sub> IU/ml.</p>b<p>By trypan blue count; visits during and following treatment.</p>c...
<p>(A) Cytokine production and CD107a mobilization of CTL lines, derived from chronically HCV infect...
<p>Resting and activated CD8 T cells were defined as CD127<sup>+</sup>CD38<sup>neg</sup> and HLA-DR<...
<p>(<b>A,B</b>) A quantitative analysis of IFN-γ production was performed in HD (n = 35, Panel A) an...
<p>CD25-depleted PBMC from patients with acute HCV infection (SR or CI) were stained with CFSE and s...
<p>(A) Pre- and on-treatment FACS density plots in response to a 5.5 hour incubation with 2 µgml<sup...
<p>Antiviral efficacy (white bars) and functional avidity (filled circles) of CTL lines, derived fro...
<p>Whole PBMC or PBMC depleted of either CD4<sup>+</sup> or CD8<sup>+</sup> T cells from 17 HCMV ser...