Effect of baicalein on ROS generation and NOX2 expression in diabetic retina.
- Amira Othman (380131)
- Saif Ahmad (371052)
- Sylvia Megyerdi (380132)
- Rene Mussell (380133)
- Karishma Choksi (380134)
- Krishna Rao Maddipati (380135)
- Ahmed Elmarakby (380136)
- Nasser Rizk (380137)
- Mohamed Al-Shabrawey (380138)
Publication date
February 2013
DOIAbstract
<p>DHE staining (A) of retinal section showed marked increase in ROS generation in diabetic mice which was prevented by baicalein. Immunofluorescence (B) and Western blot analysis of NOX2 (C) in mouse retina demonstrated marked upregulation by diabetes and this increase was significantly reduced by baicalein. *P<0.05 vs C, # P<0.05 vs D (n = 6).</p
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