[a]<p>Stern-Volmer quenching association constant (10<sup>−3</sup>Lmol<sup>−1</sup>).</p>[b]<p>Bimolecular quenching kinetic constant (10<sup>−12</sup>Lmol<sup>−1</sup>s<sup>−1</sup>) assuming τ<sub>0</sub> = 5 ns for the tryptophan fluorescence decay.</p>[c]<p>Dissociation constant (10<sup>−4 </sup>molL<sup>−1</sup>) for the protein-ligand complexes from Hill analysis of the quenching data.</p>[d]<p>Number of binding sites per molecule of protein from Hill analysis of the quenching data.</p>[e]<p>SPR steady state association equilibrium constant (10<sup>−3</sup> Lmol<sup>−1</sup>).</p
This work is a combination of three projects involving the study of a binding probe used in affinity...
Serum albumin is the main drug transporter of the bloodstream and contains two main binding sites: ...
<p>Dissociation constants (Kd) for binding of human monoclonal Abs 1_C02 and E05 to H3N2 viruses.</p
<p>Based on the good agreement between the theoretical Rmax (determined using the GE Biacore T100 so...
Interaction thermodynamics between warfarin, a very popular anticoagulant, and Sudlow I binding site...
A growing consensus is emerging that optimizing the drug–target affinity alone under equilibrium con...
<p>Association rate constants (k<sub>a</sub>), dissociation rate constants (k<sub>d</sub>), equilibr...
<p>(<b>a</b>) Reference albumin IIa site ligands warfarin (1), efavirenz (2a) and efavirenz with ami...
In the last three decades, protein and nucleic acid structure determination and comprehension of the...
<p>Solid lines represent the binding curves for six BMP-2 concentrations ranging from 0.2 to 50 nM. ...
<p>Binding parameters obtained from steady state fluorescence measurements of both DCS and PYZ inter...
<p><i>n</i> represents the number of experiments, each performed in triplicate.</p><p>Ø represents n...
High-performance affinity chromatography is used to study the binding mechanisms of thyroid hormones...
<p>Quenching of intrinsic fluorescence. (A) Azadiradione bound HPA. (B) Gedunin bound to HPA. Insets...
This article reports the interaction of rifampicin, one of the important antituberculosis drugs, wit...
This work is a combination of three projects involving the study of a binding probe used in affinity...
Serum albumin is the main drug transporter of the bloodstream and contains two main binding sites: ...
<p>Dissociation constants (Kd) for binding of human monoclonal Abs 1_C02 and E05 to H3N2 viruses.</p
<p>Based on the good agreement between the theoretical Rmax (determined using the GE Biacore T100 so...
Interaction thermodynamics between warfarin, a very popular anticoagulant, and Sudlow I binding site...
A growing consensus is emerging that optimizing the drug–target affinity alone under equilibrium con...
<p>Association rate constants (k<sub>a</sub>), dissociation rate constants (k<sub>d</sub>), equilibr...
<p>(<b>a</b>) Reference albumin IIa site ligands warfarin (1), efavirenz (2a) and efavirenz with ami...
In the last three decades, protein and nucleic acid structure determination and comprehension of the...
<p>Solid lines represent the binding curves for six BMP-2 concentrations ranging from 0.2 to 50 nM. ...
<p>Binding parameters obtained from steady state fluorescence measurements of both DCS and PYZ inter...
<p><i>n</i> represents the number of experiments, each performed in triplicate.</p><p>Ø represents n...
High-performance affinity chromatography is used to study the binding mechanisms of thyroid hormones...
<p>Quenching of intrinsic fluorescence. (A) Azadiradione bound HPA. (B) Gedunin bound to HPA. Insets...
This article reports the interaction of rifampicin, one of the important antituberculosis drugs, wit...
This work is a combination of three projects involving the study of a binding probe used in affinity...
Serum albumin is the main drug transporter of the bloodstream and contains two main binding sites: ...
<p>Dissociation constants (Kd) for binding of human monoclonal Abs 1_C02 and E05 to H3N2 viruses.</p