<p>Splenocytes from pooled naïve or mock infected and γHV68 infected B6, HELMET, and B cell−/− mice were counted and stained with antibodies against CD8, CD4, and CD19. The splenocyte numbers were the same in naïve and mock-infected mice, and data from mock infected and naïve mice were pooled. Numbers represent number of cells/spleen × 10<sup>6</sup>. The data are pooled from two to six independent experiments evaluating three to five mice per experiment.</p
<p><i>A. Weight and cellularity of WT and KO thymi and spleens.</i> Mouse number (n) in each group i...
<p>Although expansion of B- and T-cells is the major cause of splenomegaly in wild-type animals, SCI...
<p>Wild-type (WT) or TLR7-deficient mice were infected with FV. At 7 dpi, splenocytes were harvested...
<div><p>(A) Splenocytes from mock infected and γHV68 infected B6 and HELMET mice were stained with a...
<p>After TM injection at PN4, control (n = 3) and Jak2 cKO (n = 4) spleens were harvested at PN15 an...
<p><b>A)</b> Total splenocyte numbers were determined. Lines indicate the mean, and each symbol repr...
<p>(A) Single cell suspensions of spleens were stained for B cells (CD19<sup>+</sup>B220<sup>+</sup>...
<p>Splenocytes from naïve mice were stained for surface expression of FasL and the cellular composit...
<p>Splenic B cells in uninfected B6-TCR<sup>-/-</sup> mice (n = 3) and B6-TCR<sup>-/-</sup> (n = 3) ...
<p>CD4<sup>+</sup>CD69<sup>+</sup> T cells (A, B) and CD8<sup>+</sup>CD69<sup>+</sup> T cells (C, D)...
<div><p>Cells were prepared from the lungs and spleens harvested from four uninfected naïve mice or ...
<p>Following infection with V and Ts, the spleen (A), MLN and blood from three mice per group per ti...
<p>BALB/c mice were injected with 10<sup>5</sup> MACS purified CD4+ DO11.10 T cells one day prior to...
<p>A) Splenomegaly. Mice were infected i.n. with 5×10<sup>4</sup> PFU of MHV-68. At the indicated ti...
(a-i) Splenic B cells were analyzed in mice on day 100 p.i. and in age-matched controls (0d). (a) Th...
<p><i>A. Weight and cellularity of WT and KO thymi and spleens.</i> Mouse number (n) in each group i...
<p>Although expansion of B- and T-cells is the major cause of splenomegaly in wild-type animals, SCI...
<p>Wild-type (WT) or TLR7-deficient mice were infected with FV. At 7 dpi, splenocytes were harvested...
<div><p>(A) Splenocytes from mock infected and γHV68 infected B6 and HELMET mice were stained with a...
<p>After TM injection at PN4, control (n = 3) and Jak2 cKO (n = 4) spleens were harvested at PN15 an...
<p><b>A)</b> Total splenocyte numbers were determined. Lines indicate the mean, and each symbol repr...
<p>(A) Single cell suspensions of spleens were stained for B cells (CD19<sup>+</sup>B220<sup>+</sup>...
<p>Splenocytes from naïve mice were stained for surface expression of FasL and the cellular composit...
<p>Splenic B cells in uninfected B6-TCR<sup>-/-</sup> mice (n = 3) and B6-TCR<sup>-/-</sup> (n = 3) ...
<p>CD4<sup>+</sup>CD69<sup>+</sup> T cells (A, B) and CD8<sup>+</sup>CD69<sup>+</sup> T cells (C, D)...
<div><p>Cells were prepared from the lungs and spleens harvested from four uninfected naïve mice or ...
<p>Following infection with V and Ts, the spleen (A), MLN and blood from three mice per group per ti...
<p>BALB/c mice were injected with 10<sup>5</sup> MACS purified CD4+ DO11.10 T cells one day prior to...
<p>A) Splenomegaly. Mice were infected i.n. with 5×10<sup>4</sup> PFU of MHV-68. At the indicated ti...
(a-i) Splenic B cells were analyzed in mice on day 100 p.i. and in age-matched controls (0d). (a) Th...
<p><i>A. Weight and cellularity of WT and KO thymi and spleens.</i> Mouse number (n) in each group i...
<p>Although expansion of B- and T-cells is the major cause of splenomegaly in wild-type animals, SCI...
<p>Wild-type (WT) or TLR7-deficient mice were infected with FV. At 7 dpi, splenocytes were harvested...