<p>Activated B cells were loaded with HIV-1 X4 (IIIb) or HIV-1 R5 (Ba-L) for 2 h at 37 °C, extensively washed and then either cultured immediately with autologous T cells (panel A) or incubated for 2 d prior to adding autologous T cells (panel B). B cells and T cells directly loaded with HIV-1 served as controls.</p
<p>(A) Replication of HIV-1 in Huh7.5.1. Culture supernatants of RLuc and Jurkat T cells were collec...
This study examined the mechanisms underlying the intense activation of HIV-1-specific B cells obser...
<p>Resting CD4 T cells were purified from the peripheral blood by negative depletion. Cells were uns...
<div><p>(A–D) Transmission electron microscopy of HIV-1–loaded, activated B cells and DC. Activated ...
<p>(A) MDMs were infected with HIV-1 BaL for seven days, co-cultured with autologous CD4<sup>+</sup>...
(A) Experimental design. After 7 days of culture with AS1842856 (500nM) or vehicle only, PBT were in...
<p>Target CD4<sup>+</sup> T cells (1×10<sup>6</sup>) were treated for 16 h with H<sub>2</sub>O<sub>2...
<p>(<b>A</b>) To measure cell-free HIV-1 infections, we generated HIV-1<sub>GLuc</sub> by transfecti...
(A) Outline of experimental plan to enrich for latently infected cells following infection. Primary ...
HIV can be partially contained by host immunity and understanding the basis of this may inform vacci...
BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) induces a general dysregulation of immune sy...
Multiple dysfunctions take place in the B cell compartment during HIV-1 infection, comprising deplet...
HIV can be partially contained by host immunity and understanding the basis of this may inform vacci...
<p>The relative level of viral replication in TZM-bl cells was measured following incubation with su...
<p>Purified T cells from seven HIV-1 EI individuals were cocultured at 1∶1 ratio with autologous pur...
<p>(A) Replication of HIV-1 in Huh7.5.1. Culture supernatants of RLuc and Jurkat T cells were collec...
This study examined the mechanisms underlying the intense activation of HIV-1-specific B cells obser...
<p>Resting CD4 T cells were purified from the peripheral blood by negative depletion. Cells were uns...
<div><p>(A–D) Transmission electron microscopy of HIV-1–loaded, activated B cells and DC. Activated ...
<p>(A) MDMs were infected with HIV-1 BaL for seven days, co-cultured with autologous CD4<sup>+</sup>...
(A) Experimental design. After 7 days of culture with AS1842856 (500nM) or vehicle only, PBT were in...
<p>Target CD4<sup>+</sup> T cells (1×10<sup>6</sup>) were treated for 16 h with H<sub>2</sub>O<sub>2...
<p>(<b>A</b>) To measure cell-free HIV-1 infections, we generated HIV-1<sub>GLuc</sub> by transfecti...
(A) Outline of experimental plan to enrich for latently infected cells following infection. Primary ...
HIV can be partially contained by host immunity and understanding the basis of this may inform vacci...
BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) induces a general dysregulation of immune sy...
Multiple dysfunctions take place in the B cell compartment during HIV-1 infection, comprising deplet...
HIV can be partially contained by host immunity and understanding the basis of this may inform vacci...
<p>The relative level of viral replication in TZM-bl cells was measured following incubation with su...
<p>Purified T cells from seven HIV-1 EI individuals were cocultured at 1∶1 ratio with autologous pur...
<p>(A) Replication of HIV-1 in Huh7.5.1. Culture supernatants of RLuc and Jurkat T cells were collec...
This study examined the mechanisms underlying the intense activation of HIV-1-specific B cells obser...
<p>Resting CD4 T cells were purified from the peripheral blood by negative depletion. Cells were uns...